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Specific characters of objects under modeling
Thus, the methods used for formalization should allow not only the initial gene networks and their minor modifications (mutations) to be analyzed, but also the dynamics of virtually any genetic variants constructed from them to be calculated. In other words, any model of a gene network should potentially contain models of many gene networks, including those drastically different from the initial one. A generalized chemical kinetic method, developed earlier and already applied for simulating different gene networks [Bazhan et al., 1995; Belova et al., 1995], meets all these requirements. This method provides a precise and effective portrait simulation of the gene network performance patterns, as its computer realization reflects adequately the basic properties of biological systems.
Bazhan S.I., Likhoshvai V.A., Belova O.E.
Theoretical analysis of the regulation of interferon expression during priming and
blocking. Journal of Theoretical Biology, 1995, V.175, p149-160.
Belova O.E., Likhoshvai V.A., Bazhan S.I.,
Kulichkov V.A. Computer system for investigation and integrated description of
molecular-genetic system regulation of interferon induction and action. CABIOS, 1995,
V.11, No. 2, p.213-218.