Dmitry A. Afonnikov, Ms.D.
Curriculum Vitae and List of Publications
Work Experience and Current Position:
VII.1998-present - junior scientist, Laboratory of theoretical molecular biology, Institute of Cytology and Genetics SB RAS.
XI.1997-XII.1997 - visiting scientist, Molecular bioinformatic group, GBF, Braunschweig, Germany.
1994-VII.1998 - engineer, Laboratory of theoretical molecular biology, Institute of Cytology and Genetics SB RAS.
1992-1994 - probationer-researcher, Sector of Computer Analysis of genetic macromolecules, Institute of Cytology and Genetics SB RAS.
Area of Scientific interest:
Computer analysis of protein sequence and structure, biophysics, molecular biology, evolution.
Selective school of physics and mathematics, Novosibirsk, 1984 - 1985.
M. Sc. in Physics, Novosibirsk State University, 1985-1992 .
Special courses "Population genetics", Novosibirsk State University, 1991.
The principal contributor of the WWW resources:
CRASP : www-based analysis of amino acid substitution correlations in protein sequences (URL: http://wwwmgs.bionet.nsc.ru/mgs/programs/crasp/)
Conferences and Workshops:
1998 - The First International conference on Bioinformatics of Genome Regulation and Structure , Novosibirsk, Russia, August 24 - 31,1998, member of local organizing commetee, Book of reports co-editor, oral and posters presentations.
1998 - International Symposium: Protein Structure, Stability and Folding. Fundamental and Medical Aspects., Moscow, Russia, June 22-26, 1998, poster presentation.
1998 - International School "Theoretical Byophysics" , Moscow State University, Moscow, Russia, June, 16-20, report.
1997 - German conference on Bioinformatics (GCB'97), Kloster Irsee, Bavaria, Germany, 22-24 September, oral presentation.
1997 - Modern Concepts in Evolutionary Genetics, Novosibirsk, Russia, 9-12 September; poster presentation.
List of publications:
Afonnikov D.A., Kondrakhin Yu.V., Titov I.I. "Revealing of Correlated Positions of the DNA-binding region of the CREB and Ap-1 transcription factor families". Mol. Biol. (Russian), 1997, 31 (4), 741-748.
Afonnikov,D.A and Titov,I.I. (1998) Functional relationship between amino acid residues at n- and c-termini of DNA-binding regions of transcription factors CREB and AP-1 revealed by analyzing the pair correlations of amino acid substitutions. Proc. 1st Intern. Conference on Bioinformatics of Genome Regulation and Structure, Novosibirsk, Russia, 377-379 .
Afonnikov,D.A. and Wingender,E. (1998) Statistical relation between the positions of the alpha-helix in the zinc-finger DNA-binding domain: results from the phage display data analysis. Proc. 1st Intern. Conference on Bioinformatics of Genome Regulation and Structure, Novosibirsk, Russia, 380-383 .
Afonnikov,D.A., Titov,I.I., Kondrakhin,Yu.V. (1998) Correlations between positions at the N and C- ends of the DNA-binding region of the CREB and AP-1 transcription factor families reflect their functional interaction. Int. Symp. Protein Structure, Stability, and Folding. Fundamental and Medical Aspects, Book of Program and abstracts, ONTI PNC RAN, Puschino, 1998., p 114.
Afonnikov,D., Wingender,E. (1998) Positional correlation of physico-chemical characteristics within the alpha-helices of C2H2-type zinc-finger DNA-binding domains: analysis of phage display data. International School "Theoretical Byophysics", book of abstracts, p. 21.
Afonnikov,D.A., Kondrakhin,Yu.V., Titov,I.I. and Kolchanov,N.A. (1997) Detecting direct correlation between positions in multiple alignment of amino-acid sequences. In Mewes,H.W. and Frishman,D. (eds) Computer science and biology. Genome informatics:Function,structure,phylogeny, Proc. of the German Conference on Bioinformatics, 1997. pp. 87-98.
Afonnikov,D.A., Kondrakhin,Yu.V. and Titov I.I. (1997) Amino acid substitution correlations in the DNA-binding region of the CREB and Ap-1 transcription factor families. Proc. of the International conference " Modern Concepts in Evolutionary Genetics", Novosibirsk,1997, 1, p. 33-35.