Sergey V. Lavryushev

Sergey V. Lavryushev, Ms.D.

Curriculum Vitae and List of Publications

Work Experience and Current Position:

1995 - present  Program analyst,  Laboratory of Theoretical Molecular Genetics, Institute of Cytology and Genetics, Novosibirsk, Russia.
Web Master,  WWW resourse of Laboratory.

Area of Scientific interest:

Genetic text analysis, web-design, intelligent user interfaces, many-year experience (from 1987) in RT-11, MS DOS, and Windows operational systems, Fortran, Pascal, C/C++ and Perl programming languages, SRS system.

Education Background:

Full secondary school, 1979 – 1987

Special mathematical school, 1987-1988.

Special Physico-mathematical school, 1988-1989.

Novosibirsk State University (Mathematical Faculty), 1989-1998.

 

Institute of Cytology and Genetics, Novosibirsk, Russia:

The Third International Conference on Bioinformatics of Genome Regulation and Structure - Web Master and co-author of Web design

(URL:http://www.bionet.nsc.ru/meeting/bgrs2002/)

The First Workshop on Information Technologies Application to Problems of Biodiversity and Dynamics of Ecosystems in North Eurasia (WITA'2001)- Web Master and co-author of Web design

(URL: http://www.bionet.nsc.ru/meeting/bdne2001/)

THE FIRST INTERNATIONAL CONFERENCE BIODIVERSITY AND DYNAMICS OF ECOSYSTEMS IN NORTH EURASIA (BDENE-2000)- Web Master and co-author of Web design

(URL: http://www.bionet.nsc.ru/meeting/bdne2000/)

SELEX_DB: a database on selected randomized DNA/RNA sequences - Administrator of DB

(URL: http://wwwmgs.bionet.nsc.ru/mgs/systems/selex/)

The Second International Conference on Bioinformatics of Genome Regulation and Structure - Web Master and co-author of Web design

(URL: http://www.bionet.nsc.ru/bgrs2000/)

Vogis Courier (official edition of Vavilov Society of Geneticists and Breeders) - Editor of web version and Web Master, co-author of Web design

(URL: http://www.bionet.nsc.ru/vogis/)

SGS server Web design and Web Master

(URL: http://www.bionet.nsc.ru/sgs/)

Molecular-biological server - Web Master and co-author of Web design
(URL:http://wwwmgs.bionet.nsc.ru/)
The First International Conference on Bioinformatics of Genome Regulation and Structure - Web Master and Web design

(URL: http://bgrs.bionet.nsc.ru/)

Siberian Regional Center for Geneinformatics- Overal Web design

(URL: http://www.bionet.nsc.ru/SRCG/)

The co-author of the WWW resources:

Programm "POLIIIScan" co-author of programming realization
(URL: http://www.bionet.nsc.ru/ICIG/molgen/amgl/poliiiscan/)
Programm "ARGO Viewer" - Overall Web design and co-author of programming realization
(URL: http://wwwwmgs.bionet.nsc.ru/mgs/programs/argo/argo_viewer.html)
Programm "ARGO" - Overall Web design and co-author of programming realization
(URL: http://wwwmgs.bionet.nsc.ru/mgs/programs/argo/)
Programm "MMSite" - Overall Web design and co-author of programming realization
(URL: http://wwwmgs.bionet.nsc.ru/mgs/programs/mmsite/)
Programm "Multalig" - Overall Web design and co-author of programming realization
(URL: http://wwwmgs.bionet.nsc.ru/mgs/programs/multalig/)
Programm "Ppromoter recognition program" - Overall Web design and co-author of programming realization
(URL: http://wwwmgs.bionet.nsc.ru/mgs/programs/recon2/)
Programm "Recon" (program to recognize nucleosome binding sites) - Overall Web design and co-author of programming realization
(URL: http://wwwmgs.bionet.nsc.ru/mgs/programs/recon/)
Programm "SeqAnn" (activation of the TRRD database while recognizing regulatory genomic sequences) - Overall Web design and co-author of programming realization
(URL: http://wwwtest.bionet.nsc.ru/mgs/programs/seqann/)
"GenExpress"(an intellectual system for analysis of genomic regulatory sequences of humans and higher eukaryotes) - Overall Web design and programming realization
(URL: http://wwwmgs.bionet.nsc.ru/systems/GeneExpress/)
"RGSiteScan":  a program predicting the potential binding sites of 37 transcription factors, in the target DNA sequence - Overall Web design and co-author of  programming realization
(URL: http://wwwmgs.bionet.nsc.ru/mgs/programs/yura/rgscan1.html)
"RecGroup":  a program aimed on construction of Recognition groups which are used further by the RGSiteScan for final result - Overall Web design and co-author of programming realization
(URL: http://wwwmgs.bionet.nsc.ru/mgs/programs/yura/recgroup.html)

Conferences and Workshops:

 

2002-

The Third International conference on Bioinformatics of Genome Regulation and Structure(BGRS'98) Novosibirsk Russia July 14 - 20, 2002

  1. Recognition of eukaryotic promoters using genetic algorithm based on iterative discriminant analysis, Levitsky V.G.,  Katokhin A.V., Lavryushev S.V. co-author of report
  2. Geneexpress-2002: an integrated system on gene expression regulation, Kolchanov N.A., Podkolodny N.L., Ananko E.A., Ignatieva E.V., Podkolodnaya O.A., Stepanenko I.L., Merkulova T.I., Lavryushev S.V., Grigorovich D.A., Kochetov A.V., Orlova G.V., Titov I.I., Vishnevsky O.V., Orlov Yu.L. 1, Ivanisenko V.A., Vorobiev D.G., Oshchepkov D.Yu., Omelyanchuk N.A., Pozdnyakov M.A., Afonnikov D.A., Matushkin Yu.G., Likhoshvai V.A., Ratushny A.V., Katokhin A.V., Turnaev I.I., Proskura A.L., Suslov V.V., Nedosekina E.A., co-author of report

2001-

2000-

The Second International conference on Bioinformatics of Genome Regulation and Structure(BGRS'98) Novosibirsk - Altai mountains, Russia August 7 - 11,2000

  1. Activated databases on DNA sites, their structure, function and activity J.V. Ponomarenko, G.V. Orlova, M.P. Ponomarenko, S.V. Lavryushev, A.S Frolov co-author of report
  2. Integrated system on gene expression regulation GeneExpress - 2000 N.À. Kolchanov, N.L. Podkolodny, M.P. Ponomarenko, E.A. Ananko, E.V. Ignatieva, F.À. Kolpakov, V.G. Levitsky, O.A. Podkolodnaya, I.L. Stepanenko, T.I. Merkulova, D.G. Vorobiev, S.V. Lavryushev, D.A. Grigorovich, J.V. Ponomarenko, A.V. Kochetov, G.V Orlova. , Y.V. Kondrakhin, I.I. Titov, Î.V. Vishnevsky, Yu.L. Orlov, V.P. Valuev, V.A. Ivanisenko, D.Yu. Oschepkov, N.A. Omel'yanchuk, M.A. Pozdnyakov, P.S. Kosarev, T. N. Goryachkovskaya, O.N. Fokin, L.A. Kalinichenko, Yu.V. Kotlyarov co-author of report
  3. SELEX_DB: an activated database on DNA/RNA sequences obtained in SELEX-experiments J.V. Ponomarenko, G.V. Orlova, M.P. Ponomarenko, S.V. Lavryushev, S.V. Zybova, A.S. Frolov
  4. rSNP_Guide: a database documenting influence of substitutions in regulatory gene regions onto their interaction with nuclear proteins and predicting protein binding sites, damaged or appeared de novo due to these substitutions J.V. Ponomarenko, G.V. Orlova, M.P. Ponomarenko, S.V. Lavryushev, T.I. Merkulova
  5. Recognition groups: a new method for description and prediction of transcription factor binding sites Yu.V. Kondrakhin, L. Milanesi, S.V. Lavryushev, J. Schug, N.A. Kolchanov
  6. Education on the basis of the GeneExpress system: business game "Regulatory signals" M.P. Ponomarenko, J.V. Ponomarenko, S.V. Lavryushev, D.G. Vorobiev, A.V. Minina, S.A. Ivashin, Yu.I. Mikhailov
  7. Development of knowledge base on plant gene expression regulation I.L. Stepanenko, T.N. Goryachkovsky, S.S. Ibragimova, A.V. Axenovich, N.A. Omelyanchuk, S.V. Lavryushev, N.L. Podkolodny

1999 -

I-ая Всероссийская научная конференция "Электронные библиотеки: перспективные методы и технологии, электронные коллекции", 19-22 октября 1999г. Санкт-Петербург

    1. Колчанов Н.А., Лаврюшев С.В., Григорович Д.А., Пономаренко М.П., Фролрв А.С., Подколодный А.С., Колпаков Ф.А., Пономаренко Ю.В., Кочетов А.В., Ананько Е.А., Подколодная О.А., Игнатьева Е.В. ГЕНЭКСПРЕСС: электронная библиотека по стуктурам и функциям ДНК, РНК и белков //труды стр. 161-169

II съезд биофоизиков России 23-27 августа 1999г. Москва

  1. Лаврюшев С.В., Фролов А.С., Григорович Д.А., Колчанов Н.А  Активизация баз данных в рамках молекулярно-биологического сервера ИЦиГ СО РАН, тезис //тезисы докладов т.3 стр. 960-961
  2. Фролов А.С., Григорович Д.А., Лаврюшев С.В.,    Пономаренко М.П. Поиск промоторов на основе использования экспериментально информации об их структуре //тезисы докладов т.3 стр. 983-984

VII - Генетико-селекционная школа ,СО РАСХН, 19–23 апрел

  1. Н.А.Омельянчук, С.В.Лаврюшев, О.Н.Фокин, В.С.Коваль Создание селекционно-генетической базы данных co-author of report

Международное рабочее совещание по электронным публикаци EL-Pub-99

  1. Григорович Д.А., Лаврюшев С.В. Создание WWW-сайта конференции BGRS-98 co-author of report
  2. Колчанов Н.А., Иванисенко В.А., Григорович Д.А., Пономаренко М.П., Фролов А.С., Подколодный Н.Л., Колпаков Ф.А., Куропатов Д.А., Пономаренко Ю.В., Лаврюшев С.В., Кочетов А.В., Ананько Е.А., Фокин О.Н., Подколодная О.А., Игнатьева Е.В., Афонников Д.А. Компьютерная система ГЕНЭКСПРЕСС как электронная библиотека по структурам и функциям ДНК, РНК и белков co-author of report
  3. Лаврюшев С.В., Григорович Д.А. Электронная версия информационного вестника ВОГиС author of report

The Russian-British Workshop on Digital Libraries will take place on June 16-17, 1999 in Moscow, Russia
Proceedings of the Participants of the Workshop Published in the "Russian Digital Libraries Journal" (1999 - Vol. 2 - Issue 2-4)

  1. Databases on Plant Genetics and Breeding in West Siberia (Rus) V.S. Koval, N.A. Omelianchuk, S.V.Lavryushev, O.N. Fokin co-author of poster
  2. Digital Library of Genetic Markers in Different Populations of the Domestic Pig (Rus)G.V. Orlova, S.V. Nikitin, V.A. Bekenev, I.G. Gorelov, S.P. Knyazev, A.A. Khizhnyak, S.V. Lavryushev co-author of poster

 1998 -      

N.A. Kolchanov, M.P. Ponamorenko, A.E. Kel, J.V. Ponomarenko, F. A. Kolpakov, A.S. Frolov, V.V. Soloviev*, A.G. Romashchenko, E.A. Ananko, E.V. Ignatieva, O.A. Podkolodnaya, I.L. Stepanenko, O.V. Kel, T.I. Merkulova, T.N. Goryachkovskaya, A.V. Kochetov, N.L. Podkolodny, G.B. Kolesov, S.V. Lavryushev, L.L. Kisselev**, "GenExpress: an intellectual system for analysis of genomic regulatory sequences of humans and higher eukaryotes", Abstract for HUGO'98

The First International conference on Bioinformatics of Genome Regulation and Structure(BGRS'98) Novosibirsk - Altai mountains, Russia August 24 - 31,1998

  1. TRANSCRIPTION REGULATORY REGIONS DATABASE (TRRD): NEW POSSIBILITIES PROVIDED BY RELEASE 4.0. co-author of report
    KOLCHANOV N.A., IGNATIEVA E.V., KEL-MARGOULIS O.V., KEL A.E., ANANKO E.A., PODKOLODNAYA O.A., STEPANENKO I.L., MERKULOVA T.I., GORYACHKOVSKY T.N., KOLPAKOV F.A., PODKOLODNY N.L., LAVRYUSHEV S.V., GRIGOROVICH D.A., FROLOV A.S., ROMASHCHENKO A.G.
  2. GENEEXPRESS SYSTEM: DESCRIPTION, ANALYSIS, AND RECOGNITION OF REGULATORY SEQUENCES IN EUKARYOTIC GENOMES. co-author of report
    KOLCHANOV N.A., PONOMARENKO M.P., KONDRAKHIN Y.V., FROLOV A.S., KOLPAKOV F.A., KEL A.E., KEL-MARGOULIS O.V., ANANKO E.A., IGNATIEVA E.V., PODKOLODNAYA O.A., STEPANENKO I.L., MERKULOVA T.I., BABENKO V.N., VOROBIEV D.G., LAVRYUSHEV S.V., GRIGOROVICH D.A., PONOMARENKO J.V., KOCHETOV A.V., KOLESOV G.B., PODKOLODNY N.L., WINGENDER E., HAINEMEIER T., MILANESI L., SOLOVYEV V.V., OVERTON G.C.
  3. A SYSTEM FOR ACTIVATION OF THE TRRD DATABASE: FURTHER DEVELOPMENT OF GENEEXPRESS. co-author of report
    FROLOV A.S., LAVRYUSHEV S.V., VOROBIEV D.G., GRIGOROVICH D.A.

M. Ponomarenko, N. Kolchanov, A. Kel, Y. Kondrakhin, A. Frolov, F. Kolpakov, O. Kel, E. Ananko, E. Ignatieva, O. Podkolodnaya, I. Stepanenko, T. Merkulova, V. Babenko, D. Vorobiev, S. Lavryushev, J. Ponomarenko, A. Kochetov, G. Kolesov N. Podkolodny (Russia), L. Milanesi (Italy), E. Wingender (Germany), T. Heinemeyer (Germany), and V. Solovyev (United Kingdom). GeneEepress: a computer system for investigating molecular mechanisms of gene expression. Abstracts XVIIIth International Congress of Genetics, August 10-15, 1998, Beijing, China, p.62, 4S24 co-author of report

Ananko E.A., Kel A.E., Kel O.V., Ignatieva E.V., Podkolodnaya O.A., Merkulova T.I., Merkulova I.L., Stepanenko I.L., Busigina T.V., Kozlova O.N., Kochetov A.V., Kolpakov F.A., Kolesov G.B., Lavryushev S.V., Grigorovich D.A., Podkolodny N.L., Frolov A.S., Romashchenko A.G., Kolchanov N.A. Transcription regulatory regions database (TRRD) as a global information system on transcription regulation of eukaryotic genes// Abstracts of Theoretical Biophysics International School, Moscow, 1998, p. 25. co-author of report

Frolov A.S., Lavryushev S.V., Grigorovich D.A., Kel A.E., Ptitsyn A.A., Kolchanov N.A., Podkolodny N.L., Solovyev V.V., Milanesi L., Bourne P., Wingender E., Overton G.C. WWWMGS: an integrative WWW-server for molecular genetic studies //Ibid, p. 42.   co-author of report

Ignatieva E.V., Ananko E.A., Kel O.V., Podkolodnaya O.A., Merkulova T.I., Stepanenko I.L., Busigina T.V., Kozlova O.N., Kolpakov F.A., Lavryushev S.V., Grigorovich D.A., Podkolodny N.L., Frolov A.S., Kel A.E., Kolchanov N.A. LM-TRRD: the first step toward understanding complex genetic word of lipid metabolism // Ibid, p. 52.   co-author of report

Kolchanov N.A., Ponomarenko M.P., Kel A.E., Kondrakhin Yu.V., Frolov A.S., Kolpakov F.A., Goryachkovskaya T.N., Kel O.V., Ananko E.A., Ignatieva E.V., Podkolodnaya O.A., Stepanenko I.L., Merkulova T.I., Babenko V.N., Vorobiev D.G., Lavryushev S.V., Ponomarenko J.V., Kochetov A.V., Kolesov G.B., Podkolodny N.L., Milanesi L., Wingender E., Heinemeyer T., Solovyev V.V. GeneExpress: a WWW-oriented integrator for the databases and computer systems for studying the eukaryotic gene expression // Ibid, p. 57. co-author of report

Nikolay Kolchanov, Anatoly Frolov, Sergey Lavryushev, Dmitry Grigorovich, Fedor Kolpakov, Elena Ananko, Gregory Kolesov, Alexey Kochetov, Nikolay Podkolodny, Andrey Ptitsyn (1998) International conference on systems, signals, control, computers (Abstract for SSCC'98), "WWWMGS: AN INTEGRATIVE SERVER FOR MOLECULAR GENETIC STUDIES"

1996  -

International Symposium on "Teoretical and Computational Genome Research" 24-27 March, 1996  Deutsches Krebsforschungszentrum Heidelberg, Germany , "REGULATORY GENOMIC SEQUENCES, DATABASES AND TOOLS FOR ANALYSIS AND RECOGNITION",   co-author of report

Bibliography:

Articles:

  1. М.А. Поздняков, Е.Е. Витяев, Е.А. Ананько, Е.В. Игнатьева, О.А. Подколодная, Н.Л. Подколодный, С.В. Лаврюшев, Н.А. Колчанов. Сравнительный анализ методов распознавания потенциальных сайтов связывания транскрипционных факторов. // Молекулярная Биология 2001, т.35 (6), 961-969
  2. Ponomarenko JV, Merkulova TI, Vasiliev GV, Levashova ZB, Orlova GV, Lavryushev SV, Fokin ON, Ponomarenko MP, Frolov AS, Sarai A. (2001) rSNP_Guide, a database system for analysis of transcription factor binding to target sequences: application to SNPs and site-directed mutations. Nucleic Acids Res. 2001 Jan 1;29(1):312-6.
  3. Kolpakov F.A., Podkolodny N.L., Lavryushev S.V., Grigorovich D.A., Ponomarenko M.P., and Kolchanov N.A. (2000) Methods for integrating the heterogeneous molecular genetics information resources used within the digital library GENEEXPRESS. Programming (Mosk), V.1. N.3. P. 72-80. (Russ)
  4. Ponomarenko J.V., Orlova G.V., Ponomarenko M.P., Lavryushev S.V., Frolov A.S., Zybova S.V., and Kolchanov N.A. (2000) SELEX_DB: an activated database on selected randomized DNA/RNA sequences addressed to genomic sequence annotation. Nucleic Acids Res., V. 28, N. 1, P. 205-208.
  5. Колчанов Н.А., Лаврюшев С.В., Григорович Д.А., Пономаренко М.П., Фролрв А.С., Подколодный А.С., Колпаков Ф.А., Пономаренко Ю.В., Кочетов А.В., Ананько Е.А., Подколодная О.А., Игнатьева Е.В. (1999) ГЕНЭКСПРЕСС: электронная библиотека по стуктурам и функциям ДНК, РНК и белков //труды I-ой Всероссийской научной конференции "Электронные библиотеки: перспективные методы и технологии, электронные коллекции", 19-22 октября 1999г. Санкт-Петербург стр. 161-169
  6. Фролов А.С., Лаврюшев С.В., Григорович Д.А., Кель А.Э., Тицын А.А., Колчанов Н.А., Подколодный Н.Л., Соловьев В.В., Миланези Л., Борн П., Вингендер Э., Овертон К. (1999) WWWMGS: Интегрированный сервер для молекулярно-гентических исследований.// БИОФИЗИКА, 1999, том 44, вып. 5, с.832-836
  7. Kolchanov N.A., Ponomarenko M.P., Kel A.E., Kondrakhin Yu.V., Frolov A.S., Kolpakov F.A., Goriachkovsky T.N., Kel-Margulis O.V., Ananko E.A., Ignatieva E.V., Podkolodnaia O.A., Stepanenko I.L., Merkulova T.I., Babenko V.N., Vorobiev D.G., Lavryushev S.V., Ponomarenko J.V., Kochetove A.V., Kolesov G.N., Podkolodny N.L., Milanesi L., Wingender E., Heinemeier T., Solovyev V.V., Overton G.C. (1999) GeneExpress: a WWW-oriented integrator for databases and computer systems for studying the eukaryotic gene expression. Bifizika, V. 44, N. 5, P. 837-841. (Russ)
  8. N. A .Kolchanov, M. P. Ponomarenko, A. S.Frolov, E. A. Ananko, F. A. Kolpakov, E. V. Ignatieva, O. A. Podkolodnaya, T. N. Goryachkovskaya, I. L. Stepanenko, T. I. Merkulova, V. V. Babenko, Yu. V. Ponomarenko, A. V. Kochetov, N. L. Podkolodny, D. V. Vorobiev, S. V. Lavryushev, D. A. Grigorovich, Yu. V. Kondrakhin, L. Milanesi, E. Wingender, V. Solovyev and G. C. Overton (1999) Integrated databases and computer systems for studying eukaryotic gene expression   Bioinformatics V. 15, I. 7, pp. 669-686 // MEDLINE PMID: 10487874
  9. Ponomarenko M.P., Ponomarenko J.V., Frolov A.S., Lavryushev S.V., Kolchanov N.A. (1998) Computer presentation and authomated generation for the knowledge on the functional activity of the DNA and RNA molecules. In: “ Proceedings of the Institute of the Computational Mathematics and Mathematical Geophysics ”, V. 5, P. 181-198. (Russ)
  10. Kolchanov N.A., Ponomarenko M.P., Kel A. E., Kondrakhin Yu. V., Frolov A. S., Kolpakov F. A., Kel O. V., Ananko E. A., Ignatieva E.V., Podkolodnaya O. A., Stepanenko I. L., Merkulova T. I., Babenko V. N., Vorobiev D.G, Lavryushev S.V., Ponomarenko Yu. V., Kochetov A. V., Kolesov G.B., Podkolodny N. L., Milanesi L., Wingender E., Heinemeyer T., Solovyev V.V. (1998) GeneExpress: a computer system for description, analysis, and recognition of regulatory sequences of the eukaryotic genome. ISMB, V. 6, P. 95-104.// MEDLINE PMID: 9783214; UI: 98456543

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