by Kel-Margoulis O.V., okel@bionet.nsc.ru
55 vertebrate genes
E2F/pRB pathway
Genes for transcription factors regulating G0/G1 transition
I. CELL CYCLE CONTROLLING GENES
E2F/pRB pathway
Genes of cyclin-dependent kinases |
|
| p34 cdc2 gene | Human |
| cdc2 gene | Rat |
| cdc7 gene | Mouse |
p53 pathway
| p53 gene | Human |
| p53 gene | Mouse |
| mdm2 gene | Mouse |
| p14ARF gene | Human |
Genes for transcription factors regulating G0/G1 transition
members of Myc family |
|
|---|---|
| c-myc gene | Human |
| c-myc gene | Mouse |
| N-myc gene | Mouse |
members of AP-1 family |
|
| c-fos | Human |
| c-fos | Mouse |
| c-jun | Human |
| junB | Mouse |
| fosB | Mouse |
members of Myb family |
|
| B-myb | Mouse |
Enzymes |
|
Organism |
|
|---|---|
| DNA polymerase a | Human |
| DNA polymerase b | Mouse |
| CAD carbomoyl-phosphate synthase{glutamine-hydrolyzing}/ aspartate carbomoyltransferase/dihydroorotase gene | Hamster |
| DHFR dihydrofolate reductase gene | Hamster |
| DHFR | Human |
| DHFR | Mouse |
| TK thymidine kinase gene | Human |
| TK | Mouse |
| Histones | |
| H2A1 histone gene | Human |
| H2A.X histone | Mouse |
| Genes involved in the initiation of DNA replication | |
| cdc6 gene | Human |
| orc1 gene | Human |
| Others | |
| PCNA (proliferative cell nuclear antigene p120 gene) | Mouse |
| PCNA | Human |
| UDG | Human |
| Htf9/RanBP1 | Mouse |
| Ad type 2 EIIaE1 | Ad type 2 |
| Ad type 5 E1A | Ad type 5 |
| EBNA 1 | Epstein-Barr virus |