Approaches to the prediction of the functional activity of sites from their nucleotide sequences


Reference Site Activity Method
M.E. Mulligan et al., 1984, E.coli promoter Association rate Homology
Nucleic Acids Res., 12, 789   Constant, Kbk2 Score
G. Stormo, et al., 1986, 1) su2-suppression, Frequency




Nucleic Acids Res., 14, 6661 2) 2AP-mutagenesis Frequency matrix


Berg and von Hippel, 1987, 1) E.coli promoter, Constant, Kbk2 Statistical
J. Mol. Biol., 193, 723 2) CRP-binding site Affinity Mechanics
J. Jonsson et al., 1993, E.coli promoters Promoter Neural
Nucleic Acids Res., 21, 733   Strength networks
D. Barrick et al., 1994 E.coli ribosome Translation Multiple
Nucleic Acids Res., 22, 1287 Binding site Activity efficiency regression
R.J. Kraus, et al., 1996, 1) INR-element Affinity Neural
Nucleic Acids Res., 24, 1531 2) TATA box Affinity networks