16 highly correlated pairs from the work of Clarke [4] are represented in the first column.
The functional relationship between the residues at these positions (as inferred in [4]) are represented in second column: ± - salt bridge; P - interaction with phosphate backbone ; n - network of correlation betwen the residues of H3 helix in the magor groove of the DNA; ? - functional relationship is unclear.
Partial correlation coefficients calculated by our approach with respect to isoelectric point (rij (pI)) and side chain volume (rij (V)) characteristics are represented in the third and fourth columns, correspondingly. The correlation coefficients above 99.9% significance threshold (0.182) are in bold.
Homeodomain position pairs |
Functional relationship |
rij.g (pI) |
19-30 |
± |
-0.33319 |
28-54 |
? |
-0.08526 |
44-46 |
n |
-0.16912 |
8-43 |
? |
+0.07930 |
46-47 |
n |
+0.11221 |
26-46 |
n |
-0.25538 |
26-47 |
n |
+0.02062 |
44-47 |
n |
+0.09480 |
46-50 |
n |
+0.02793 |
26-44 |
n |
+0.26786 |
12-50 |
? |
+0.03061 |
17-52 |
± |
-0.27367 |
31-42 |
P |
-0.29562 |
6-47 |
? |
-0.02190 |
8-25 |
? |
+0.32777 |
46-54 |
n |
-0.11031 |