CRASP |
Pairwise positional correlation estimation results. |
MULTIPLE ALIGNMENT OF "HMEN_DROME_455 " AND HOMOLOGOUS SEQUENCES. NUMBER OF SEQUENCES: 372. ALIGNMENT LENGTH: 74. AMINO ACID PHYSICO-CHEMICAL CHARACTERISTICS: Isoelectric point. REFERENCE: White A et al.; Principles of Biochemistry;. WEIGHTS: according to Felsenstein(1985),Am.Nat.,125,1-15.
MATRIX TYPE: Linear correlation coefficient matrix. NUMBER OF ANALYSED POSITIONS: 47.
Crit.Value (99.9%): rc=0.171078
Color scheme for matrix elements:
r>+rc
r<-rc
|r|<rc
| R- 3 | P- 4 | R- 5 | T- 6 | A- 7 | F- 8 | S- 9 | S- 10 | E- 11 | Q- 12 | L- 13 | A- 14 | R- 15 | K- 17 | R- 18 | E- 19 | N- 21 | E- 22 | N- 23 | R- 24 | Y- 25 | L- 26 | T- 27 | E- 28 | R- 29 | R- 30 | R- 31 | Q- 32 | Q- 33 | L- 34 | S- 35 | S- 36 | E- 37 | L- 38 | G- 39 | L- 40 | N- 41 | E- 42 | A- 43 | Q- 44 | I- 45 | K- 46 | I- 47 | Q- 50 | K- 52 | A- 54 | I- 56 | |
| R- 3 | +1.0000 | -0.1413 | +0.1072 | -0.0704 | -0.1435 | -0.0272 | -0.1128 | +0.0275 | +0.0097 | -0.0076 | +0.0387 | +0.0282 | +0.0161 | +0.0186 | -0.0982 | -0.0102 | +0.0510 | -0.0037 | -0.0133 | +0.0391 | +0.0090 | -0.0279 | -0.1000 | +0.0151 | +0.0572 | +0.0042 | -0.0393 | -0.0230 | -0.0503 | +0.0813 | +0.0006 | +0.0003 | +0.0043 | -0.0427 | -0.0060 | +0.0256 | -0.0268 | +0.0461 | -0.0525 | +0.0116 | -0.0172 | -0.0061 | +0.0526 | +0.0239 | -0.0411 | +0.0406 | -0.0404 |
| P- 4 | -0.1413 | +1.0000 | -0.0922 | +0.2415 | +0.0752 | +0.0888 | +0.0276 | +0.0121 | +0.0384 | +0.0335 | +0.0054 | -0.0093 | -0.0428 | +0.0578 | +0.0372 | -0.0652 | +0.0495 | +0.0107 | +0.0728 | -0.0312 | +0.0611 | +0.0214 | +0.0287 | +0.0082 | -0.2084 | -0.0167 | +0.0367 | +0.0389 | +0.0893 | -0.1148 | -0.0222 | +0.0292 | -0.0375 | -0.0526 | +0.0398 | -0.0379 | +0.0124 | +0.0560 | -0.1101 | -0.0346 | -0.0226 | +0.0212 | +0.0146 | -0.1659 | -0.0922 | -0.0296 | +0.1232 |
| R- 5 | +0.1072 | -0.0922 | +1.0000 | +0.0029 | -0.0981 | +0.2173 | -0.0163 | +0.0191 | +0.0120 | +0.0035 | +0.0122 | +0.0103 | +0.0180 | -0.0035 | -0.0285 | -0.0288 | -0.0104 | +0.0441 | -0.0169 | -0.0193 | -0.0023 | +0.0125 | +0.0061 | +0.0915 | -0.1239 | +0.0116 | -0.0735 | -0.0236 | -0.0164 | +0.1221 | +0.0003 | -0.0198 | +0.0148 | +0.0014 | +0.0375 | -0.0314 | -0.0015 | +0.0074 | -0.0460 | +0.0078 | -0.0158 | -0.0223 | +0.0300 | +0.0039 | -0.0198 | -0.0031 | +0.0116 |
| T- 6 | -0.0704 | +0.2415 | +0.0029 | +1.0000 | +0.1047 | -0.0467 | +0.0079 | +0.0277 | -0.0122 | -0.0828 | -0.0472 | -0.0792 | -0.0078 | +0.0088 | -0.0408 | -0.0270 | +0.0311 | -0.0088 | -0.0138 | -0.0856 | -0.0621 | +0.0390 | +0.0172 | +0.0273 | +0.0008 | +0.0425 | +0.0542 | +0.0410 | +0.0927 | +0.0234 | -0.0218 | -0.0587 | +0.0319 | -0.1219 | -0.0189 | -0.0415 | +0.0142 | -0.0472 | -0.0169 | -0.0462 | -0.0119 | -0.0326 | -0.0258 | -0.0036 | -0.0015 | +0.0415 | +0.1328 |
| A- 7 | -0.1435 | +0.0752 | -0.0981 | +0.1047 | +1.0000 | -0.0314 | +0.1179 | -0.0357 | -0.0320 | -0.0888 | -0.0716 | +0.0970 | -0.0947 | +0.0599 | +0.0699 | +0.0685 | -0.0736 | +0.0259 | +0.0081 | +0.0220 | -0.1089 | +0.0924 | +0.1958 | -0.0370 | -0.0595 | -0.0590 | +0.0468 | +0.1461 | -0.0013 | -0.0077 | -0.0160 | -0.0117 | +0.0197 | -0.0411 | -0.0009 | -0.1095 | +0.0052 | -0.1581 | +0.2293 | -0.0758 | +0.0050 | +0.0257 | +0.0594 | +0.0367 | -0.0410 | +0.1379 | +0.0712 |
| F- 8 | -0.0272 | +0.0888 | +0.2173 | -0.0467 | -0.0314 | +1.0000 | +0.0140 | +0.0605 | +0.0471 | -0.0713 | +0.1761 | -0.0213 | -0.0190 | +0.1648 | +0.0485 | +0.0288 | +0.0184 | -0.0091 | +0.0495 | +0.0597 | +0.3854 | +0.0548 | +0.0288 | +0.3322 | +0.0460 | +0.1025 | +0.1678 | -0.0301 | +0.0326 | +0.0300 | +0.0049 | -0.0385 | -0.0569 | +0.0159 | -0.0234 | +0.0171 | +0.0644 | +0.1100 | +0.0702 | -0.0546 | +0.0047 | +0.1034 | +0.0963 | -0.0089 | -0.0723 | -0.1038 | -0.0507 |
| S- 9 | -0.1128 | +0.0276 | -0.0163 | +0.0079 | +0.1179 | +0.0140 | +1.0000 | +0.0455 | -0.0124 | -0.0270 | -0.1119 | -0.0970 | +0.0673 | +0.1146 | -0.0265 | +0.0045 | -0.0091 | -0.0403 | +0.0275 | -0.0046 | -0.1276 | -0.0207 | +0.0226 | -0.0140 | -0.0016 | +0.0176 | +0.0762 | +0.1329 | +0.0135 | -0.0471 | -0.0161 | -0.0097 | +0.0154 | -0.0579 | +0.1048 | -0.0505 | +0.1115 | -0.0388 | +0.1173 | -0.0471 | +0.0471 | -0.0240 | +0.0190 | +0.0014 | -0.0071 | +0.0908 | +0.0272 |
| S- 10 | +0.0275 | +0.0121 | +0.0191 | +0.0277 | -0.0357 | +0.0605 | +0.0455 | +1.0000 | +0.0243 | +0.0196 | -0.1068 | -0.1338 | -0.0485 | -0.0372 | +0.0191 | +0.0187 | +0.0786 | -0.0078 | +0.0560 | +0.0333 | -0.0481 | -0.0098 | +0.0230 | +0.0814 | +0.0488 | +0.0387 | +0.0586 | -0.0278 | -0.0780 | +0.0536 | +0.0161 | +0.0341 | -0.0047 | -0.0571 | +0.0444 | -0.0159 | -0.0491 | -0.0440 | +0.0011 | +0.0438 | +0.0378 | +0.0392 | -0.0135 | +0.0202 | +0.0079 | -0.0392 | +0.0405 |
| E- 11 | +0.0097 | +0.0384 | +0.0120 | -0.0122 | -0.0320 | +0.0471 | -0.0124 | +0.0243 | +1.0000 | +0.0407 | +0.0009 | -0.0126 | -0.0959 | +0.0457 | -0.0474 | -0.0378 | -0.0685 | +0.0167 | +0.0585 | +0.0765 | +0.1173 | +0.0502 | -0.0166 | +0.0417 | +0.0249 | +0.0384 | +0.0202 | -0.0097 | -0.0147 | -0.0110 | -0.0216 | -0.0646 | -0.0195 | -0.0004 | -0.0615 | +0.0390 | -0.0585 | -0.0041 | +0.0529 | -0.0219 | +0.0359 | +0.0696 | -0.0541 | -0.0432 | +0.0799 | -0.0635 | +0.0210 |
| Q- 12 | -0.0076 | +0.0335 | +0.0035 | -0.0828 | -0.0888 | -0.0713 | -0.0270 | +0.0196 | +0.0407 | +1.0000 | -0.0024 | -0.0682 | +0.0111 | -0.0274 | -0.0147 | +0.0298 | +0.0749 | +0.0196 | -0.0176 | -0.0028 | -0.0188 | -0.0574 | -0.0142 | -0.0528 | -0.0438 | -0.0937 | +0.0247 | -0.0120 | -0.0111 | -0.1754 | +0.0021 | +0.1027 | -0.0384 | +0.0286 | -0.0099 | +0.0129 | -0.1948 | +0.0519 | -0.0932 | +0.0173 | +0.0148 | +0.0506 | +0.0434 | -0.0051 | +0.0987 | +0.0244 | -0.0106 |
| L- 13 | +0.0387 | +0.0054 | +0.0122 | -0.0472 | -0.0716 | +0.1761 | -0.1119 | -0.1068 | +0.0009 | -0.0024 | +1.0000 | +0.1854 | +0.0109 | +0.0409 | -0.0039 | -0.0409 | -0.0007 | +0.0092 | +0.0303 | -0.0111 | +0.2074 | -0.0036 | -0.0084 | -0.0103 | +0.0648 | +0.0231 | -0.0451 | -0.0117 | -0.2399 | +0.0260 | +0.0227 | -0.0659 | -0.0562 | -0.0565 | -0.0431 | +0.0536 | +0.0222 | +0.0663 | -0.1261 | -0.0285 | -0.0280 | +0.0635 | +0.0452 | -0.0132 | -0.1219 | -0.0412 | +0.0053 |
| A- 14 | +0.0282 | -0.0093 | +0.0103 | -0.0792 | +0.0970 | -0.0213 | -0.0970 | -0.1338 | -0.0126 | -0.0682 | +0.1854 | +1.0000 | -0.0392 | +0.0072 | -0.0274 | -0.0454 | -0.1859 | -0.0481 | +0.0499 | +0.0406 | +0.0757 | -0.0209 | -0.0073 | +0.0002 | -0.0164 | -0.0131 | -0.0641 | +0.1226 | +0.0215 | +0.0522 | -0.0091 | +0.0274 | +0.0051 | -0.0343 | -0.0295 | +0.0184 | +0.1499 | +0.0577 | +0.1154 | -0.0488 | -0.0122 | +0.0150 | +0.0583 | -0.0448 | -0.1428 | +0.0240 | -0.0508 |
| R- 15 | +0.0161 | -0.0428 | +0.0180 | -0.0078 | -0.0947 | -0.0190 | +0.0673 | -0.0485 | -0.0959 | +0.0111 | +0.0109 | -0.0392 | +1.0000 | +0.1308 | -0.2051 | -0.1627 | -0.0867 | +0.0467 | -0.1368 | -0.1565 | -0.0134 | -0.1825 | +0.0735 | -0.1017 | +0.0359 | -0.0157 | +0.0297 | +0.0684 | +0.0966 | -0.0507 | +0.0368 | -0.0228 | -0.2432 | -0.0102 | -0.0085 | +0.0158 | +0.0419 | -0.0588 | -0.1217 | -0.0818 | +0.0334 | +0.0398 | +0.0102 | -0.0089 | -0.0286 | -0.0640 | -0.1226 |
| K- 17 | +0.0186 | +0.0578 | -0.0035 | +0.0088 | +0.0599 | +0.1648 | +0.1146 | -0.0372 | +0.0457 | -0.0274 | +0.0409 | +0.0072 | +0.1308 | +1.0000 | +0.0143 | -0.0141 | -0.1141 | -0.0778 | -0.0105 | +0.0265 | +0.1239 | +0.1160 | +0.0649 | -0.0839 | +0.0932 | +0.0208 | -0.0195 | -0.0361 | -0.0321 | +0.0150 | -0.0061 | -0.0047 | -0.0723 | +0.0223 | +0.0106 | -0.0188 | -0.0385 | -0.0093 | +0.1455 | -0.1028 | +0.0331 | -0.0140 | +0.0052 | +0.0381 | -0.2500 | -0.1002 | -0.0314 |
| R- 18 | -0.0982 | +0.0372 | -0.0285 | -0.0408 | +0.0699 | +0.0485 | -0.0265 | +0.0191 | -0.0474 | -0.0147 | -0.0039 | -0.0274 | -0.2051 | +0.0143 | +1.0000 | +0.0733 | -0.0799 | -0.0841 | +0.0580 | +0.0901 | -0.0082 | -0.0448 | -0.0205 | +0.0114 | +0.0462 | -0.0603 | +0.0093 | -0.0128 | -0.0030 | -0.0699 | -0.0189 | +0.0370 | -0.0535 | +0.0726 | -0.0052 | -0.0435 | -0.0048 | -0.0439 | +0.0340 | -0.0171 | +0.0342 | +0.0222 | +0.0211 | -0.1209 | +0.0396 | -0.0215 | -0.0161 |
| E- 19 | -0.0102 | -0.0652 | -0.0288 | -0.0270 | +0.0685 | +0.0288 | +0.0045 | +0.0187 | -0.0378 | +0.0298 | -0.0409 | -0.0454 | -0.1627 | -0.0141 | +0.0733 | +1.0000 | +0.0587 | -0.0865 | -0.1392 | +0.0722 | +0.0087 | +0.0722 | +0.0494 | -0.0710 | +0.0738 | -0.2831 | -0.0429 | -0.0301 | -0.0998 | -0.0478 | +0.0944 | -0.0203 | -0.1048 | +0.0214 | +0.0683 | -0.0241 | -0.0193 | +0.0632 | -0.0023 | +0.0052 | -0.0332 | -0.0156 | -0.0258 | +0.0355 | +0.0182 | +0.0352 | -0.0368 |
| N- 21 | +0.0510 | +0.0495 | -0.0104 | +0.0311 | -0.0736 | +0.0184 | -0.0091 | +0.0786 | -0.0685 | +0.0749 | -0.0007 | -0.1859 | -0.0867 | -0.1141 | -0.0799 | +0.0587 | +1.0000 | -0.1245 | +0.0396 | -0.0027 | -0.0070 | -0.0584 | +0.0422 | +0.0568 | +0.0638 | +0.0432 | +0.0474 | -0.0912 | -0.1144 | -0.1132 | -0.0087 | -0.0754 | +0.0364 | -0.0045 | +0.0424 | +0.0311 | -0.0833 | +0.1260 | -0.1157 | +0.0051 | +0.0457 | +0.0233 | +0.1082 | +0.0123 | +0.0147 | +0.0761 | -0.0525 |
| E- 22 | -0.0037 | +0.0107 | +0.0441 | -0.0088 | +0.0259 | -0.0091 | -0.0403 | -0.0078 | +0.0167 | +0.0196 | +0.0092 | -0.0481 | +0.0467 | -0.0778 | -0.0841 | -0.0865 | -0.1245 | +1.0000 | -0.0433 | -0.0441 | -0.0417 | -0.0381 | -0.0134 | +0.0530 | -0.0643 | -0.0735 | +0.0503 | +0.0152 | -0.0466 | +0.0998 | +0.0128 | -0.0411 | -0.0397 | -0.0840 | +0.0070 | -0.0167 | +0.0223 | -0.0477 | +0.0002 | +0.0304 | -0.0285 | +0.0745 | -0.0606 | +0.0225 | +0.0436 | -0.0508 | -0.0046 |
| N- 23 | -0.0133 | +0.0728 | -0.0169 | -0.0138 | +0.0081 | +0.0495 | +0.0275 | +0.0560 | +0.0585 | -0.0176 | +0.0303 | +0.0499 | -0.1368 | -0.0105 | +0.0580 | -0.1392 | +0.0396 | -0.0433 | +1.0000 | -0.0572 | +0.0761 | -0.0699 | +0.0138 | -0.0604 | +0.0859 | -0.1256 | +0.0437 | -0.0028 | +0.0178 | -0.0184 | +0.0094 | -0.0404 | +0.1097 | -0.0328 | +0.0384 | +0.0237 | -0.0304 | -0.0463 | +0.0164 | -0.1003 | -0.0008 | +0.1042 | +0.0459 | -0.0288 | -0.0032 | -0.0041 | +0.1295 |
| R- 24 | +0.0391 | -0.0312 | -0.0193 | -0.0856 | +0.0220 | +0.0597 | -0.0046 | +0.0333 | +0.0765 | -0.0028 | -0.0111 | +0.0406 | -0.1565 | +0.0265 | +0.0901 | +0.0722 | -0.0027 | -0.0441 | -0.0572 | +1.0000 | -0.0541 | -0.0126 | -0.0435 | -0.1112 | +0.1461 | -0.0490 | -0.0150 | -0.0080 | -0.0303 | +0.0434 | -0.0119 | +0.0329 | -0.0087 | +0.0371 | -0.0021 | +0.0099 | +0.0546 | -0.0030 | +0.0447 | +0.0074 | -0.0138 | -0.0179 | -0.0783 | +0.1618 | +0.0270 | +0.0175 | -0.0796 |
| Y- 25 | +0.0090 | +0.0611 | -0.0023 | -0.0621 | -0.1089 | +0.3854 | -0.1276 | -0.0481 | +0.1173 | -0.0188 | +0.2074 | +0.0757 | -0.0134 | +0.1239 | -0.0082 | +0.0087 | -0.0070 | -0.0417 | +0.0761 | -0.0541 | +1.0000 | +0.1001 | -0.0622 | +0.1439 | -0.0621 | +0.1217 | +0.0351 | +0.0357 | +0.0229 | +0.0005 | +0.0108 | -0.0911 | +0.0026 | +0.0284 | -0.0261 | +0.0581 | -0.2024 | +0.0412 | -0.0391 | -0.0636 | +0.0382 | +0.2058 | +0.0872 | -0.0810 | +0.0900 | -0.1332 | -0.1456 |
| L- 26 | -0.0279 | +0.0214 | +0.0125 | +0.0390 | +0.0924 | +0.0548 | -0.0207 | -0.0098 | +0.0502 | -0.0574 | -0.0036 | -0.0209 | -0.1825 | +0.1160 | -0.0448 | +0.0722 | -0.0584 | -0.0381 | -0.0699 | -0.0126 | +0.1001 | +1.0000 | -0.1685 | -0.0494 | -0.0702 | +0.0248 | -0.0974 | -0.0394 | +0.0171 | +0.0156 | -0.0213 | -0.0346 | +0.0262 | -0.0133 | -0.0528 | -0.0426 | +0.0020 | +0.1348 | +0.0193 | +0.2917 | +0.0235 | -0.2745 | +0.0260 | +0.0459 | -0.0705 | +0.0332 | +0.0107 |
| T- 27 | -0.1000 | +0.0287 | +0.0061 | +0.0172 | +0.1958 | +0.0288 | +0.0226 | +0.0230 | -0.0166 | -0.0142 | -0.0084 | -0.0073 | +0.0735 | +0.0649 | -0.0205 | +0.0494 | +0.0422 | -0.0134 | +0.0138 | -0.0435 | -0.0622 | -0.1685 | +1.0000 | +0.0075 | -0.0208 | -0.1292 | -0.0343 | -0.0823 | -0.0714 | +0.0192 | -0.0180 | +0.1002 | -0.0740 | +0.0521 | +0.0598 | -0.0327 | -0.1571 | -0.1176 | +0.0312 | -0.1442 | +0.0678 | -0.0119 | -0.0603 | -0.0873 | -0.0953 | +0.0110 | -0.0487 |
| E- 28 | +0.0151 | +0.0082 | +0.0915 | +0.0273 | -0.0370 | +0.3322 | -0.0140 | +0.0814 | +0.0417 | -0.0528 | -0.0103 | +0.0002 | -0.1017 | -0.0839 | +0.0114 | -0.0710 | +0.0568 | +0.0530 | -0.0604 | -0.1112 | +0.1439 | -0.0494 | +0.0075 | +1.0000 | +0.0254 | +0.2483 | +0.2116 | +0.0385 | -0.1017 | -0.0152 | +0.0069 | -0.0676 | -0.0086 | +0.0121 | -0.0465 | -0.0056 | -0.0412 | -0.0687 | +0.1307 | -0.0338 | -0.0189 | -0.0197 | +0.0625 | -0.0395 | +0.0520 | -0.0694 | +0.0084 |
| R- 29 | +0.0572 | -0.2084 | -0.1239 | +0.0008 | -0.0595 | +0.0460 | -0.0016 | +0.0488 | +0.0249 | -0.0438 | +0.0648 | -0.0164 | +0.0359 | +0.0932 | +0.0462 | +0.0738 | +0.0638 | -0.0643 | +0.0859 | +0.1461 | -0.0621 | -0.0702 | -0.0208 | +0.0254 | +1.0000 | -0.0712 | -0.0051 | -0.0438 | -0.1030 | +0.0232 | +0.0697 | +0.0349 | -0.1289 | -0.0093 | +0.0124 | +0.0405 | +0.1263 | +0.0210 | +0.0164 | -0.0497 | +0.0117 | +0.0419 | +0.0591 | +0.0156 | -0.0795 | +0.0335 | +0.0109 |
| R- 30 | +0.0042 | -0.0167 | +0.0116 | +0.0425 | -0.0590 | +0.1025 | +0.0176 | +0.0387 | +0.0384 | -0.0937 | +0.0231 | -0.0131 | -0.0157 | +0.0208 | -0.0603 | -0.2831 | +0.0432 | -0.0735 | -0.1256 | -0.0490 | +0.1217 | +0.0248 | -0.1292 | +0.2483 | -0.0712 | +1.0000 | +0.0350 | -0.0174 | -0.1388 | +0.0129 | -0.0704 | -0.0369 | +0.0074 | +0.0121 | -0.0963 | +0.0402 | +0.1168 | -0.0376 | +0.0369 | +0.0203 | +0.0570 | +0.0482 | +0.0406 | +0.0395 | +0.0196 | +0.0424 | +0.1118 |
| R- 31 | -0.0393 | +0.0367 | -0.0735 | +0.0542 | +0.0468 | +0.1678 | +0.0762 | +0.0586 | +0.0202 | +0.0247 | -0.0451 | -0.0641 | +0.0297 | -0.0195 | +0.0093 | -0.0429 | +0.0474 | +0.0503 | +0.0437 | -0.0150 | +0.0351 | -0.0974 | -0.0343 | +0.2116 | -0.0051 | +0.0350 | +1.0000 | -0.0299 | -0.0371 | -0.0118 | +0.0081 | +0.0040 | -0.0315 | -0.1472 | +0.0122 | -0.0225 | -0.0269 | -0.3388 | -0.0281 | +0.0903 | +0.0206 | +0.0188 | +0.0070 | -0.0738 | +0.1798 | -0.1062 | +0.0182 |
| Q- 32 | -0.0230 | +0.0389 | -0.0236 | +0.0410 | +0.1461 | -0.0301 | +0.1329 | -0.0278 | -0.0097 | -0.0120 | -0.0117 | +0.1226 | +0.0684 | -0.0361 | -0.0128 | -0.0301 | -0.0912 | +0.0152 | -0.0028 | -0.0080 | +0.0357 | -0.0394 | -0.0823 | +0.0385 | -0.0438 | -0.0174 | -0.0299 | +1.0000 | +0.1431 | -0.0326 | -0.0255 | -0.1563 | +0.0207 | +0.0214 | +0.0157 | -0.0565 | +0.0281 | -0.0793 | +0.0214 | -0.1268 | +0.0505 | +0.0617 | -0.0064 | -0.1093 | +0.0288 | +0.1124 | +0.0335 |
| Q- 33 | -0.0503 | +0.0893 | -0.0164 | +0.0927 | -0.0013 | +0.0326 | +0.0135 | -0.0780 | -0.0147 | -0.0111 | -0.2399 | +0.0215 | +0.0966 | -0.0321 | -0.0030 | -0.0998 | -0.1144 | -0.0466 | +0.0178 | -0.0303 | +0.0229 | +0.0171 | -0.0714 | -0.1017 | -0.1030 | -0.1388 | -0.0371 | +0.1431 | +1.0000 | +0.0277 | -0.0113 | -0.1362 | -0.1054 | +0.0004 | -0.0401 | +0.0101 | +0.1058 | -0.0029 | +0.0302 | -0.0593 | -0.0307 | -0.0472 | -0.0092 | -0.0334 | +0.0051 | -0.0374 | -0.0984 |
| L- 34 | +0.0813 | -0.1148 | +0.1221 | +0.0234 | -0.0077 | +0.0300 | -0.0471 | +0.0536 | -0.0110 | -0.1754 | +0.0260 | +0.0522 | -0.0507 | +0.0150 | -0.0699 | -0.0478 | -0.1132 | +0.0998 | -0.0184 | +0.0434 | +0.0005 | +0.0156 | +0.0192 | -0.0152 | +0.0232 | +0.0129 | -0.0118 | -0.0326 | +0.0277 | +1.0000 | +0.0026 | +0.0741 | +0.0389 | -0.0202 | +0.0099 | -0.0233 | +0.0008 | +0.0581 | +0.0340 | +0.0077 | -0.0128 | -0.0077 | -0.0715 | +0.0166 | -0.0111 | -0.0092 | +0.0665 |
| S- 35 | +0.0006 | -0.0222 | +0.0003 | -0.0218 | -0.0160 | +0.0049 | -0.0161 | +0.0161 | -0.0216 | +0.0021 | +0.0227 | -0.0091 | +0.0368 | -0.0061 | -0.0189 | +0.0944 | -0.0087 | +0.0128 | +0.0094 | -0.0119 | +0.0108 | -0.0213 | -0.0180 | +0.0069 | +0.0697 | -0.0704 | +0.0081 | -0.0255 | -0.0113 | +0.0026 | +1.0000 | +0.0014 | -0.0120 | -0.0407 | +0.0061 | +0.0031 | +0.0019 | -0.0052 | +0.0089 | -0.0009 | +0.0096 | +0.0021 | +0.0153 | -0.0044 | -0.0070 | -0.0158 | -0.0063 |
| S- 36 | +0.0003 | +0.0292 | -0.0198 | -0.0587 | -0.0117 | -0.0385 | -0.0097 | +0.0341 | -0.0646 | +0.1027 | -0.0659 | +0.0274 | -0.0228 | -0.0047 | +0.0370 | -0.0203 | -0.0754 | -0.0411 | -0.0404 | +0.0329 | -0.0911 | -0.0346 | +0.1002 | -0.0676 | +0.0349 | -0.0369 | +0.0040 | -0.1563 | -0.1362 | +0.0741 | +0.0014 | +1.0000 | -0.1056 | -0.0158 | -0.0216 | -0.0148 | +0.0023 | -0.0424 | +0.0008 | -0.0075 | -0.0027 | -0.0232 | -0.0259 | -0.0217 | +0.0111 | -0.0280 | -0.0216 |
| E- 37 | +0.0043 | -0.0375 | +0.0148 | +0.0319 | +0.0197 | -0.0569 | +0.0154 | -0.0047 | -0.0195 | -0.0384 | -0.0562 | +0.0051 | -0.2432 | -0.0723 | -0.0535 | -0.1048 | +0.0364 | -0.0397 | +0.1097 | -0.0087 | +0.0026 | +0.0262 | -0.0740 | -0.0086 | -0.1289 | +0.0074 | -0.0315 | +0.0207 | -0.1054 | +0.0389 | -0.0120 | -0.1056 | +1.0000 | +0.0749 | -0.0452 | -0.0015 | +0.0293 | +0.0318 | -0.0495 | +0.0752 | -0.0189 | -0.0466 | +0.0160 | +0.0510 | -0.0629 | +0.1070 | +0.0411 |
| L- 38 | -0.0427 | -0.0526 | +0.0014 | -0.1219 | -0.0411 | +0.0159 | -0.0579 | -0.0571 | -0.0004 | +0.0286 | -0.0565 | -0.0343 | -0.0102 | +0.0223 | +0.0726 | +0.0214 | -0.0045 | -0.0840 | -0.0328 | +0.0371 | +0.0284 | -0.0133 | +0.0521 | +0.0121 | -0.0093 | +0.0121 | -0.1472 | +0.0214 | +0.0004 | -0.0202 | -0.0407 | -0.0158 | +0.0749 | +1.0000 | +0.0213 | +0.0156 | +0.0211 | +0.1121 | -0.0310 | +0.0323 | +0.2185 | +0.0550 | +0.0113 | +0.0638 | -0.0430 | -0.0566 | -0.0582 |
| G- 39 | -0.0060 | +0.0398 | +0.0375 | -0.0189 | -0.0009 | -0.0234 | +0.1048 | +0.0444 | -0.0615 | -0.0099 | -0.0431 | -0.0295 | -0.0085 | +0.0106 | -0.0052 | +0.0683 | +0.0424 | +0.0070 | +0.0384 | -0.0021 | -0.0261 | -0.0528 | +0.0598 | -0.0465 | +0.0124 | -0.0963 | +0.0122 | +0.0157 | -0.0401 | +0.0099 | +0.0061 | -0.0216 | -0.0452 | +0.0213 | +1.0000 | -0.0193 | -0.0374 | -0.0573 | -0.0303 | -0.0419 | +0.0006 | +0.0059 | +0.0250 | +0.0425 | +0.0073 | +0.0055 | -0.0995 |
| L- 40 | +0.0256 | -0.0379 | -0.0314 | -0.0415 | -0.1095 | +0.0171 | -0.0505 | -0.0159 | +0.0390 | +0.0129 | +0.0536 | +0.0184 | +0.0158 | -0.0188 | -0.0435 | -0.0241 | +0.0311 | -0.0167 | +0.0237 | +0.0099 | +0.0581 | -0.0426 | -0.0327 | -0.0056 | +0.0405 | +0.0402 | -0.0225 | -0.0565 | +0.0101 | -0.0233 | +0.0031 | -0.0148 | -0.0015 | +0.0156 | -0.0193 | +1.0000 | +0.0421 | +0.0158 | -0.0192 | +0.0403 | -0.0011 | -0.0234 | -0.0400 | +0.0240 | -0.0317 | -0.0729 | -0.0385 |
| N- 41 | -0.0268 | +0.0124 | -0.0015 | +0.0142 | +0.0052 | +0.0644 | +0.1115 | -0.0491 | -0.0585 | -0.1948 | +0.0222 | +0.1499 | +0.0419 | -0.0385 | -0.0048 | -0.0193 | -0.0833 | +0.0223 | -0.0304 | +0.0546 | -0.2024 | +0.0020 | -0.1571 | -0.0412 | +0.1263 | +0.1168 | -0.0269 | +0.0281 | +0.1058 | +0.0008 | +0.0019 | +0.0023 | +0.0293 | +0.0211 | -0.0374 | +0.0421 | +1.0000 | +0.0027 | +0.0005 | -0.0177 | -0.0326 | -0.1167 | -0.0531 | +0.1856 | -0.2920 | +0.0255 | +0.0465 |
| E- 42 | +0.0461 | +0.0560 | +0.0074 | -0.0472 | -0.1581 | +0.1100 | -0.0388 | -0.0440 | -0.0041 | +0.0519 | +0.0663 | +0.0577 | -0.0588 | -0.0093 | -0.0439 | +0.0632 | +0.1260 | -0.0477 | -0.0463 | -0.0030 | +0.0412 | +0.1348 | -0.1176 | -0.0687 | +0.0210 | -0.0376 | -0.3388 | -0.0793 | -0.0029 | +0.0581 | -0.0052 | -0.0424 | +0.0318 | +0.1121 | -0.0573 | +0.0158 | +0.0027 | +1.0000 | +0.0094 | -0.1391 | -0.0525 | -0.0024 | +0.0669 | -0.0468 | -0.2573 | +0.1237 | -0.0430 |
| A- 43 | -0.0525 | -0.1101 | -0.0460 | -0.0169 | +0.2293 | +0.0702 | +0.1173 | +0.0011 | +0.0529 | -0.0932 | -0.1261 | +0.1154 | -0.1217 | +0.1455 | +0.0340 | -0.0023 | -0.1157 | +0.0002 | +0.0164 | +0.0447 | -0.0391 | +0.0193 | +0.0312 | +0.1307 | +0.0164 | +0.0369 | -0.0281 | +0.0214 | +0.0302 | +0.0340 | +0.0089 | +0.0008 | -0.0495 | -0.0310 | -0.0303 | -0.0192 | +0.0005 | +0.0094 | +1.0000 | -0.0981 | -0.0014 | -0.0698 | -0.0058 | -0.0020 | -0.1169 | +0.0765 | -0.0637 |
| Q- 44 | +0.0116 | -0.0346 | +0.0078 | -0.0462 | -0.0758 | -0.0546 | -0.0471 | +0.0438 | -0.0219 | +0.0173 | -0.0285 | -0.0488 | -0.0818 | -0.1028 | -0.0171 | +0.0052 | +0.0051 | +0.0304 | -0.1003 | +0.0074 | -0.0636 | +0.2917 | -0.1442 | -0.0338 | -0.0497 | +0.0203 | +0.0903 | -0.1268 | -0.0593 | +0.0077 | -0.0009 | -0.0075 | +0.0752 | +0.0323 | -0.0419 | +0.0403 | -0.0177 | -0.1391 | -0.0981 | +1.0000 | -0.0468 | -0.2231 | +0.0522 | +0.0486 | +0.0743 | -0.0423 | +0.0167 |
| I- 45 | -0.0172 | -0.0226 | -0.0158 | -0.0119 | +0.0050 | +0.0047 | +0.0471 | +0.0378 | +0.0359 | +0.0148 | -0.0280 | -0.0122 | +0.0334 | +0.0331 | +0.0342 | -0.0332 | +0.0457 | -0.0285 | -0.0008 | -0.0138 | +0.0382 | +0.0235 | +0.0678 | -0.0189 | +0.0117 | +0.0570 | +0.0206 | +0.0505 | -0.0307 | -0.0128 | +0.0096 | -0.0027 | -0.0189 | +0.2185 | +0.0006 | -0.0011 | -0.0326 | -0.0525 | -0.0014 | -0.0468 | +1.0000 | +0.0167 | +0.0072 | -0.0205 | +0.0402 | -0.0005 | -0.0086 |
| K- 46 | -0.0061 | +0.0212 | -0.0223 | -0.0326 | +0.0257 | +0.1034 | -0.0240 | +0.0392 | +0.0696 | +0.0506 | +0.0635 | +0.0150 | +0.0398 | -0.0140 | +0.0222 | -0.0156 | +0.0233 | +0.0745 | +0.1042 | -0.0179 | +0.2058 | -0.2745 | -0.0119 | -0.0197 | +0.0419 | +0.0482 | +0.0188 | +0.0617 | -0.0472 | -0.0077 | +0.0021 | -0.0232 | -0.0466 | +0.0550 | +0.0059 | -0.0234 | -0.1167 | -0.0024 | -0.0698 | -0.2231 | +0.0167 | +1.0000 | +0.1076 | -0.0113 | +0.3380 | -0.1163 | +0.0293 |
| I- 47 | +0.0526 | +0.0146 | +0.0300 | -0.0258 | +0.0594 | +0.0963 | +0.0190 | -0.0135 | -0.0541 | +0.0434 | +0.0452 | +0.0583 | +0.0102 | +0.0052 | +0.0211 | -0.0258 | +0.1082 | -0.0606 | +0.0459 | -0.0783 | +0.0872 | +0.0260 | -0.0603 | +0.0625 | +0.0591 | +0.0406 | +0.0070 | -0.0064 | -0.0092 | -0.0715 | +0.0153 | -0.0259 | +0.0160 | +0.0113 | +0.0250 | -0.0400 | -0.0531 | +0.0669 | -0.0058 | +0.0522 | +0.0072 | +0.1076 | +1.0000 | -0.0283 | -0.0134 | +0.0743 | -0.0007 |
| Q- 50 | +0.0239 | -0.1659 | +0.0039 | -0.0036 | +0.0367 | -0.0089 | +0.0014 | +0.0202 | -0.0432 | -0.0051 | -0.0132 | -0.0448 | -0.0089 | +0.0381 | -0.1209 | +0.0355 | +0.0123 | +0.0225 | -0.0288 | +0.1618 | -0.0810 | +0.0459 | -0.0873 | -0.0395 | +0.0156 | +0.0395 | -0.0738 | -0.1093 | -0.0334 | +0.0166 | -0.0044 | -0.0217 | +0.0510 | +0.0638 | +0.0425 | +0.0240 | +0.1856 | -0.0468 | -0.0020 | +0.0486 | -0.0205 | -0.0113 | -0.0283 | +1.0000 | +0.0497 | +0.2597 | +0.0130 |
| K- 52 | -0.0411 | -0.0922 | -0.0198 | -0.0015 | -0.0410 | -0.0723 | -0.0071 | +0.0079 | +0.0799 | +0.0987 | -0.1219 | -0.1428 | -0.0286 | -0.2500 | +0.0396 | +0.0182 | +0.0147 | +0.0436 | -0.0032 | +0.0270 | +0.0900 | -0.0705 | -0.0953 | +0.0520 | -0.0795 | +0.0196 | +0.1798 | +0.0288 | +0.0051 | -0.0111 | -0.0070 | +0.0111 | -0.0629 | -0.0430 | +0.0073 | -0.0317 | -0.2920 | -0.2573 | -0.1169 | +0.0743 | +0.0402 | +0.3380 | -0.0134 | +0.0497 | +1.0000 | -0.0798 | -0.0618 |
| A- 54 | +0.0406 | -0.0296 | -0.0031 | +0.0415 | +0.1379 | -0.1038 | +0.0908 | -0.0392 | -0.0635 | +0.0244 | -0.0412 | +0.0240 | -0.0640 | -0.1002 | -0.0215 | +0.0352 | +0.0761 | -0.0508 | -0.0041 | +0.0175 | -0.1332 | +0.0332 | +0.0110 | -0.0694 | +0.0335 | +0.0424 | -0.1062 | +0.1124 | -0.0374 | -0.0092 | -0.0158 | -0.0280 | +0.1070 | -0.0566 | +0.0055 | -0.0729 | +0.0255 | +0.1237 | +0.0765 | -0.0423 | -0.0005 | -0.1163 | +0.0743 | +0.2597 | -0.0798 | +1.0000 | +0.0662 |
| I- 56 | -0.0404 | +0.1232 | +0.0116 | +0.1328 | +0.0712 | -0.0507 | +0.0272 | +0.0405 | +0.0210 | -0.0106 | +0.0053 | -0.0508 | -0.1226 | -0.0314 | -0.0161 | -0.0368 | -0.0525 | -0.0046 | +0.1295 | -0.0796 | -0.1456 | +0.0107 | -0.0487 | +0.0084 | +0.0109 | +0.1118 | +0.0182 | +0.0335 | -0.0984 | +0.0665 | -0.0063 | -0.0216 | +0.0411 | -0.0582 | -0.0995 | -0.0385 | +0.0465 | -0.0430 | -0.0637 | +0.0167 | -0.0086 | +0.0293 | -0.0007 | +0.0130 | -0.0618 | +0.0662 | +1.0000 |