CRASP |
Pairwise positional correlation estimation results. |
MULTIPLE ALIGNMENT OF "HMEN_DROME_455 " AND HOMOLOGOUS SEQUENCES. NUMBER OF SEQUENCES: 372. ALIGNMENT LENGTH: 74. AMINO ACID PHYSICO-CHEMICAL CHARACTERISTICS: Isoelectric point. REFERENCE: White A et al.; Principles of Biochemistry;. WEIGHTS: according to Felsenstein(1985),Am.Nat.,125,1-15.
MATRIX TYPE: Partial correlation coefficient matrix. NUMBER OF ANALYSED POSITIONS: 47. Crit.Value (99.9%): rc=0.182170
Color scheme for matrix elements:
r>+rc
r<-rc
|r|<rc
| R- 3 | P- 4 | R- 5 | T- 6 | A- 7 | F- 8 | S- 9 | S- 10 | E- 11 | Q- 12 | L- 13 | A- 14 | R- 15 | K- 17 | R- 18 | E- 19 | N- 21 | E- 22 | N- 23 | R- 24 | Y- 25 | L- 26 | T- 27 | E- 28 | R- 29 | R- 30 | R- 31 | Q- 32 | Q- 33 | L- 34 | S- 35 | S- 36 | E- 37 | L- 38 | G- 39 | L- 40 | N- 41 | E- 42 | A- 43 | Q- 44 | I- 45 | K- 46 | I- 47 | Q- 50 | K- 52 | A- 54 | I- 56 | |
| R- 3 | +1.0000 | -0.1005 | +0.0809 | -0.0364 | -0.0780 | -0.0455 | -0.0977 | +0.0286 | +0.0145 | -0.0276 | +0.0012 | +0.0085 | -0.0103 | +0.0608 | -0.0895 | -0.0030 | +0.0355 | -0.0124 | +0.0040 | +0.0449 | -0.0050 | -0.0417 | -0.0991 | +0.0416 | +0.0048 | -0.0254 | -0.0155 | +0.0046 | -0.0240 | +0.0555 | -0.0141 | +0.0091 | -0.0213 | -0.0532 | -0.0040 | +0.0075 | -0.0267 | -0.0037 | -0.0516 | +0.0029 | +0.0086 | +0.0130 | +0.0541 | -0.0198 | -0.0554 | +0.0609 | -0.0348 |
| P- 4 | -0.1005 | +1.0000 | -0.1426 | +0.2502 | +0.0545 | +0.0865 | +0.0019 | +0.0205 | +0.0518 | +0.0255 | -0.0120 | +0.0011 | -0.0478 | +0.0969 | +0.0081 | -0.0777 | +0.0666 | +0.0299 | +0.0600 | +0.0699 | +0.0404 | -0.0232 | -0.0147 | +0.0438 | -0.2744 | -0.0683 | -0.0170 | -0.0033 | +0.0452 | -0.1073 | +0.0076 | +0.0763 | -0.0911 | -0.0267 | +0.0811 | -0.0215 | +0.0679 | +0.0571 | -0.1612 | +0.0284 | -0.0151 | +0.0348 | +0.0049 | -0.1751 | -0.0799 | +0.0435 | +0.1116 |
| R- 5 | +0.0809 | -0.1426 | +1.0000 | +0.0688 | -0.0858 | +0.2841 | +0.0073 | -0.0096 | +0.0333 | +0.0433 | -0.0544 | +0.0500 | +0.0172 | -0.0088 | -0.0020 | -0.0380 | +0.0144 | +0.0211 | -0.0010 | -0.0076 | -0.1076 | +0.0098 | -0.0221 | +0.0339 | -0.1866 | -0.0480 | -0.1576 | -0.0268 | -0.0594 | +0.1113 | +0.0118 | -0.0317 | -0.0199 | -0.0018 | +0.0473 | -0.0345 | -0.0069 | -0.0942 | -0.0797 | -0.0157 | -0.0140 | -0.0171 | +0.0312 | -0.0450 | -0.0155 | +0.0328 | +0.0228 |
| T- 6 | -0.0364 | +0.2502 | +0.0688 | +1.0000 | +0.0637 | -0.0777 | -0.0427 | +0.0205 | -0.0162 | -0.0764 | +0.0169 | -0.0714 | +0.0025 | +0.0137 | -0.0321 | +0.0190 | +0.0187 | -0.0220 | -0.0474 | -0.0757 | -0.0353 | +0.0373 | +0.0205 | +0.0223 | +0.1054 | +0.0492 | +0.0507 | +0.0185 | +0.0993 | +0.0314 | -0.0236 | -0.0402 | +0.0659 | -0.0952 | -0.0215 | -0.0133 | -0.0162 | -0.0081 | +0.0079 | -0.0566 | +0.0123 | -0.0204 | -0.0219 | +0.0443 | +0.0318 | +0.0035 | +0.0713 |
| A- 7 | -0.0780 | +0.0545 | -0.0858 | +0.0637 | +1.0000 | +0.0263 | +0.0534 | -0.0436 | -0.0263 | -0.0551 | -0.0423 | +0.0935 | -0.0542 | -0.0034 | +0.0601 | +0.0446 | -0.0099 | +0.0405 | -0.0304 | +0.0122 | -0.1013 | +0.1742 | +0.1882 | -0.0634 | -0.0540 | -0.0336 | +0.0498 | +0.1198 | -0.0377 | +0.0106 | -0.0024 | -0.0280 | +0.0177 | -0.0067 | -0.0347 | -0.0508 | -0.0276 | -0.1680 | +0.1840 | -0.0840 | -0.0245 | +0.1027 | +0.0972 | +0.0531 | -0.0521 | +0.0844 | +0.0371 |
| F- 8 | -0.0455 | +0.0865 | +0.2841 | -0.0777 | +0.0263 | +1.0000 | +0.0137 | +0.0665 | -0.0209 | -0.0514 | +0.1823 | -0.1329 | +0.0326 | +0.1333 | +0.0425 | +0.0848 | -0.0118 | +0.0018 | +0.0659 | +0.1313 | +0.3278 | +0.0433 | +0.1160 | +0.3031 | +0.0510 | +0.0334 | +0.2204 | -0.0090 | +0.1436 | -0.0107 | -0.0154 | +0.0495 | +0.0055 | -0.0148 | -0.0050 | +0.0083 | +0.1508 | +0.2059 | +0.0793 | +0.0420 | +0.0154 | +0.0870 | +0.0505 | +0.0380 | -0.0269 | -0.0379 | +0.0018 |
| S- 9 | -0.0977 | +0.0019 | +0.0073 | -0.0427 | +0.0534 | +0.0137 | +1.0000 | +0.0350 | +0.0036 | -0.0114 | -0.0377 | -0.1253 | +0.0571 | +0.1394 | -0.0498 | +0.0213 | -0.0131 | -0.0505 | +0.0462 | +0.0087 | -0.0895 | -0.0244 | +0.0138 | +0.0006 | -0.0314 | +0.0156 | +0.0619 | +0.1245 | -0.0121 | -0.0340 | -0.0188 | +0.0118 | +0.0386 | -0.0749 | +0.1082 | -0.0184 | +0.1353 | +0.0481 | +0.0903 | +0.0066 | +0.0531 | -0.0117 | +0.0330 | -0.0489 | +0.0687 | +0.0725 | +0.0099 |
| S- 10 | +0.0286 | +0.0205 | -0.0096 | +0.0205 | -0.0436 | +0.0665 | +0.0350 | +1.0000 | +0.0193 | +0.0306 | -0.1136 | -0.0843 | -0.0108 | -0.0675 | +0.0272 | +0.0175 | +0.0347 | -0.0275 | +0.0600 | +0.0254 | -0.0602 | +0.0192 | +0.0158 | +0.0433 | +0.0281 | +0.0355 | -0.0025 | +0.0240 | -0.0712 | +0.0741 | +0.0141 | +0.0133 | -0.0131 | -0.0825 | +0.0285 | -0.0140 | -0.0571 | -0.0366 | +0.0010 | +0.0489 | +0.0489 | +0.0739 | -0.0188 | +0.0494 | -0.0867 | -0.0595 | -0.0035 |
| E- 11 | +0.0145 | +0.0518 | +0.0333 | -0.0162 | -0.0263 | -0.0209 | +0.0036 | +0.0193 | +1.0000 | +0.0475 | -0.0194 | -0.0280 | -0.1040 | +0.0334 | -0.0915 | -0.0461 | -0.0940 | +0.0001 | +0.0348 | +0.0750 | +0.0780 | +0.0414 | +0.0196 | +0.0114 | +0.0480 | +0.0049 | +0.0124 | -0.0206 | -0.0293 | -0.0246 | -0.0184 | -0.0864 | -0.0415 | +0.0013 | -0.0592 | +0.0340 | +0.0033 | +0.0082 | +0.0481 | -0.0236 | +0.0321 | +0.0333 | -0.0496 | -0.0437 | +0.0621 | -0.0204 | +0.0109 |
| Q- 12 | -0.0276 | +0.0255 | +0.0433 | -0.0764 | -0.0551 | -0.0514 | -0.0114 | +0.0306 | +0.0475 | +1.0000 | +0.0412 | -0.0223 | -0.0147 | +0.0297 | -0.0279 | +0.0174 | +0.0340 | +0.0464 | -0.0270 | +0.0023 | -0.0354 | -0.0532 | -0.0316 | -0.0219 | -0.0205 | -0.0508 | +0.0623 | +0.0237 | +0.0496 | -0.1844 | -0.0019 | +0.1292 | -0.0145 | +0.0279 | -0.0224 | +0.0165 | -0.1603 | +0.0747 | -0.0474 | +0.0138 | +0.0120 | +0.0086 | +0.0358 | +0.0306 | +0.0332 | +0.0380 | +0.0239 |
| L- 13 | +0.0012 | -0.0120 | -0.0544 | +0.0169 | -0.0423 | +0.1823 | -0.0377 | -0.1136 | -0.0194 | +0.0412 | +1.0000 | +0.1624 | -0.0450 | -0.0467 | +0.0090 | -0.1138 | -0.0096 | -0.0213 | -0.0174 | -0.0391 | +0.1209 | -0.0129 | -0.0176 | -0.0963 | +0.0190 | -0.0603 | -0.0672 | +0.0153 | -0.3202 | +0.0548 | +0.0242 | -0.1355 | -0.1306 | -0.0713 | -0.0560 | +0.0259 | +0.0090 | -0.0449 | -0.1426 | -0.0226 | -0.0230 | +0.0225 | +0.0139 | +0.0214 | -0.1197 | -0.0221 | -0.0139 |
| A- 14 | +0.0085 | +0.0011 | +0.0500 | -0.0714 | +0.0935 | -0.1329 | -0.1253 | -0.0843 | -0.0280 | -0.0223 | +0.1624 | +1.0000 | -0.0573 | +0.0008 | -0.0761 | -0.0255 | -0.1793 | -0.0990 | +0.0640 | +0.0652 | +0.0892 | -0.0544 | +0.0251 | +0.0679 | -0.0429 | -0.0316 | +0.0167 | +0.1105 | +0.0129 | +0.0256 | -0.0171 | +0.0476 | -0.0189 | -0.0744 | +0.0023 | +0.0127 | +0.1671 | +0.0839 | +0.0935 | +0.0424 | +0.0389 | +0.0529 | +0.0691 | -0.0497 | -0.0694 | +0.0185 | -0.0674 |
| R- 15 | -0.0103 | -0.0478 | +0.0172 | +0.0025 | -0.0542 | +0.0326 | +0.0571 | -0.0108 | -0.1040 | -0.0147 | -0.0450 | -0.0573 | +1.0000 | +0.1185 | -0.2281 | -0.2154 | -0.1185 | -0.0152 | -0.1550 | -0.1676 | +0.0095 | -0.1815 | +0.0377 | -0.1331 | +0.0356 | -0.0673 | +0.0333 | +0.0671 | -0.0170 | -0.0597 | +0.0456 | -0.0807 | -0.2742 | +0.0063 | -0.0655 | +0.0006 | +0.0384 | -0.0274 | -0.1454 | -0.0304 | +0.0233 | -0.0048 | +0.0392 | +0.0107 | -0.0265 | -0.0089 | -0.1286 |
| K- 17 | +0.0608 | +0.0969 | -0.0088 | +0.0137 | -0.0034 | +0.1333 | +0.1394 | -0.0675 | +0.0334 | +0.0297 | -0.0467 | +0.0008 | +0.1185 | +1.0000 | +0.0556 | -0.0201 | -0.0878 | -0.0744 | -0.0426 | -0.0102 | +0.0605 | +0.1496 | +0.0122 | -0.1586 | +0.1193 | +0.0453 | +0.0080 | -0.0301 | -0.0837 | +0.0378 | -0.0100 | -0.0424 | -0.0186 | +0.0174 | -0.0148 | -0.0266 | -0.1675 | -0.1155 | +0.1228 | -0.1117 | +0.0023 | +0.0419 | -0.0075 | +0.1378 | -0.2737 | -0.1485 | -0.0307 |
| R- 18 | -0.0895 | +0.0081 | -0.0020 | -0.0321 | +0.0601 | +0.0425 | -0.0498 | +0.0272 | -0.0915 | -0.0279 | +0.0090 | -0.0761 | -0.2281 | +0.0556 | +1.0000 | +0.0020 | -0.1278 | -0.0841 | +0.0339 | +0.0603 | -0.0211 | -0.1007 | -0.0752 | +0.0081 | +0.0171 | -0.0612 | -0.0232 | -0.0370 | -0.0190 | -0.0693 | -0.0239 | -0.0039 | -0.1051 | +0.0675 | -0.0233 | -0.0318 | +0.0360 | -0.0389 | -0.0257 | -0.0041 | +0.0384 | -0.0080 | +0.0285 | -0.1532 | +0.0430 | +0.0457 | -0.0488 |
| E- 19 | -0.0030 | -0.0777 | -0.0380 | +0.0190 | +0.0446 | +0.0848 | +0.0213 | +0.0175 | -0.0461 | +0.0174 | -0.1138 | -0.0255 | -0.2154 | -0.0201 | +0.0020 | +1.0000 | +0.0220 | -0.1246 | -0.2140 | -0.0157 | +0.0851 | +0.0216 | +0.0163 | -0.0666 | +0.0123 | -0.3332 | -0.0286 | -0.0090 | -0.1897 | -0.0315 | +0.0912 | -0.1012 | -0.1850 | +0.0166 | +0.0232 | -0.0028 | +0.0684 | +0.0116 | -0.0378 | -0.0210 | -0.0386 | +0.0039 | -0.0261 | +0.0069 | +0.0209 | +0.0336 | +0.0091 |
| N- 21 | +0.0355 | +0.0666 | +0.0144 | +0.0187 | -0.0099 | -0.0118 | -0.0131 | +0.0347 | -0.0940 | +0.0340 | -0.0096 | -0.1793 | -0.1185 | -0.0878 | -0.1278 | +0.0220 | +1.0000 | -0.1358 | +0.0443 | +0.0078 | -0.0153 | -0.0730 | +0.0591 | +0.0269 | +0.0643 | +0.0441 | +0.0732 | -0.0441 | -0.0866 | -0.0837 | -0.0185 | -0.1043 | -0.0202 | -0.0404 | +0.0096 | +0.0256 | -0.0316 | +0.1309 | -0.0824 | +0.0149 | +0.0679 | +0.0155 | +0.0866 | +0.0132 | -0.0198 | +0.0401 | -0.1099 |
| E- 22 | -0.0124 | +0.0299 | +0.0211 | -0.0220 | +0.0405 | +0.0018 | -0.0505 | -0.0275 | +0.0001 | +0.0464 | -0.0213 | -0.0990 | -0.0152 | -0.0744 | -0.0841 | -0.1246 | -0.1358 | +1.0000 | -0.0494 | -0.0355 | -0.0239 | -0.0213 | -0.0218 | +0.0628 | -0.0557 | -0.1420 | +0.0146 | +0.0133 | -0.1206 | +0.1047 | +0.0082 | -0.0891 | -0.0758 | -0.0893 | +0.0018 | -0.0089 | +0.0636 | -0.0064 | +0.0101 | +0.0429 | +0.0135 | +0.1009 | -0.0405 | +0.0287 | -0.0262 | -0.0268 | -0.0448 |
| N- 23 | +0.0040 | +0.0600 | -0.0010 | -0.0474 | -0.0304 | +0.0659 | +0.0462 | +0.0600 | +0.0348 | -0.0270 | -0.0174 | +0.0640 | -0.1550 | -0.0426 | +0.0339 | -0.2140 | +0.0443 | -0.0494 | +1.0000 | -0.1107 | +0.0783 | -0.0263 | +0.0019 | -0.1238 | +0.1157 | -0.1846 | +0.0304 | -0.0297 | -0.0081 | -0.0266 | +0.0153 | -0.0575 | +0.0662 | -0.0064 | +0.0245 | +0.0281 | -0.0234 | -0.0804 | +0.0337 | -0.1012 | -0.0141 | +0.0430 | +0.0221 | +0.0237 | -0.0098 | -0.0005 | +0.1323 |
| R- 24 | +0.0449 | +0.0699 | -0.0076 | -0.0757 | +0.0122 | +0.1313 | +0.0087 | +0.0254 | +0.0750 | +0.0023 | -0.0391 | +0.0652 | -0.1676 | -0.0102 | +0.0603 | -0.0157 | +0.0078 | -0.0355 | -0.1107 | +1.0000 | -0.0633 | -0.0552 | -0.0380 | -0.1799 | +0.1604 | -0.0143 | +0.0062 | +0.0435 | -0.0470 | +0.0415 | -0.0094 | -0.0155 | -0.0191 | +0.0292 | -0.0359 | -0.0021 | -0.0215 | -0.0304 | +0.0195 | -0.0222 | -0.0253 | -0.0524 | -0.0680 | +0.1700 | +0.0402 | -0.0401 | -0.0912 |
| Y- 25 | -0.0050 | +0.0404 | -0.1076 | -0.0353 | -0.1013 | +0.3278 | -0.0895 | -0.0602 | +0.0780 | -0.0354 | +0.1209 | +0.0892 | +0.0095 | +0.0605 | -0.0211 | +0.0851 | -0.0153 | -0.0239 | +0.0783 | -0.0633 | +1.0000 | +0.1318 | -0.0717 | +0.0197 | -0.0555 | +0.1317 | -0.0320 | +0.0446 | +0.0519 | +0.0215 | +0.0157 | -0.0368 | +0.0578 | +0.0081 | -0.0074 | +0.0448 | -0.2278 | -0.0672 | -0.0542 | -0.0701 | +0.0245 | +0.1355 | +0.0318 | -0.0170 | +0.0164 | -0.0404 | -0.1541 |
| L- 26 | -0.0417 | -0.0232 | +0.0098 | +0.0373 | +0.1742 | +0.0433 | -0.0244 | +0.0192 | +0.0414 | -0.0532 | -0.0129 | -0.0544 | -0.1815 | +0.1496 | -0.1007 | +0.0216 | -0.0730 | -0.0213 | -0.0263 | -0.0552 | +0.1318 | +1.0000 | -0.1501 | -0.0534 | -0.0373 | -0.0011 | -0.0873 | -0.0057 | +0.0001 | -0.0223 | -0.0195 | -0.0065 | -0.0669 | -0.0413 | -0.0273 | -0.0599 | +0.0103 | +0.1562 | -0.0524 | +0.2679 | +0.0729 | -0.2554 | +0.0206 | +0.0137 | +0.0492 | -0.0004 | -0.0064 |
| T- 27 | -0.0991 | -0.0147 | -0.0221 | +0.0205 | +0.1882 | +0.1160 | +0.0138 | +0.0158 | +0.0196 | -0.0316 | -0.0176 | +0.0251 | +0.0377 | +0.0122 | -0.0752 | +0.0163 | +0.0591 | -0.0218 | +0.0019 | -0.0380 | -0.0717 | -0.1501 | +1.0000 | +0.0256 | -0.0485 | -0.1089 | -0.1224 | -0.1429 | -0.0706 | +0.0451 | -0.0314 | +0.0584 | -0.0712 | +0.0765 | +0.0144 | -0.0113 | -0.1752 | -0.1815 | -0.0617 | -0.0992 | +0.0531 | -0.0317 | -0.0686 | -0.0936 | -0.1286 | +0.0604 | -0.0610 |
| E- 28 | +0.0416 | +0.0438 | +0.0339 | +0.0223 | -0.0634 | +0.3031 | +0.0006 | +0.0433 | +0.0114 | -0.0219 | -0.0963 | +0.0679 | -0.1331 | -0.1586 | +0.0081 | -0.0666 | +0.0269 | +0.0628 | -0.1238 | -0.1799 | +0.0197 | -0.0534 | +0.0256 | +1.0000 | +0.1032 | +0.1747 | +0.1333 | +0.0803 | -0.1286 | -0.0297 | +0.0259 | -0.0851 | -0.0256 | +0.0741 | -0.0560 | -0.0177 | -0.0907 | -0.0702 | +0.1248 | -0.0959 | -0.0732 | -0.1368 | +0.0440 | +0.0496 | +0.0300 | -0.0853 | -0.0090 |
| R- 29 | +0.0048 | -0.2744 | -0.1866 | +0.1054 | -0.0540 | +0.0510 | -0.0314 | +0.0281 | +0.0480 | -0.0205 | +0.0190 | -0.0429 | +0.0356 | +0.1193 | +0.0171 | +0.0123 | +0.0643 | -0.0557 | +0.1157 | +0.1604 | -0.0555 | -0.0373 | -0.0485 | +0.1032 | +1.0000 | -0.1274 | -0.0467 | -0.0265 | -0.0980 | +0.0331 | +0.0546 | +0.0272 | -0.1526 | -0.0151 | +0.0234 | +0.0281 | +0.1520 | -0.0107 | -0.0427 | +0.0070 | +0.0164 | +0.0681 | +0.0724 | -0.1000 | -0.0518 | +0.0916 | +0.0296 |
| R- 30 | -0.0254 | -0.0683 | -0.0480 | +0.0492 | -0.0336 | +0.0334 | +0.0156 | +0.0355 | +0.0049 | -0.0508 | -0.0603 | -0.0316 | -0.0673 | +0.0453 | -0.0612 | -0.3332 | +0.0441 | -0.1420 | -0.1846 | -0.0143 | +0.1317 | -0.0011 | -0.1089 | +0.1747 | -0.1274 | +1.0000 | -0.0531 | -0.0519 | -0.2006 | +0.0181 | -0.0405 | -0.0553 | -0.1059 | +0.0094 | -0.0576 | +0.0374 | +0.1765 | -0.0649 | +0.0109 | +0.0009 | +0.0446 | +0.0649 | +0.0198 | -0.0350 | +0.0210 | +0.1065 | +0.1052 |
| R- 31 | -0.0155 | -0.0170 | -0.1576 | +0.0507 | +0.0498 | +0.2204 | +0.0619 | -0.0025 | +0.0124 | +0.0623 | -0.0672 | +0.0167 | +0.0333 | +0.0080 | -0.0232 | -0.0286 | +0.0732 | +0.0146 | +0.0304 | +0.0062 | -0.0320 | -0.0873 | -0.1224 | +0.1333 | -0.0467 | -0.0531 | +1.0000 | -0.0854 | -0.0650 | +0.0494 | -0.0012 | -0.0200 | -0.0214 | -0.1021 | +0.0056 | -0.0254 | +0.0114 | -0.2956 | -0.0657 | +0.0591 | +0.0328 | -0.0413 | -0.0051 | -0.1057 | +0.0778 | -0.0093 | +0.0009 |
| Q- 32 | +0.0046 | -0.0033 | -0.0268 | +0.0185 | +0.1198 | -0.0090 | +0.1245 | +0.0240 | -0.0206 | +0.0237 | +0.0153 | +0.1105 | +0.0671 | -0.0301 | -0.0370 | -0.0090 | -0.0441 | +0.0133 | -0.0297 | +0.0435 | +0.0446 | -0.0057 | -0.1429 | +0.0803 | -0.0265 | -0.0519 | -0.0854 | +1.0000 | +0.0939 | -0.0140 | -0.0253 | -0.1289 | +0.0169 | +0.0644 | +0.0207 | -0.0300 | +0.0121 | -0.1231 | -0.0392 | -0.1030 | +0.0378 | +0.0347 | -0.0400 | -0.1725 | +0.0177 | +0.1546 | +0.0413 |
| Q- 33 | -0.0240 | +0.0452 | -0.0594 | +0.0993 | -0.0377 | +0.1436 | -0.0121 | -0.0712 | -0.0293 | +0.0496 | -0.3202 | +0.0129 | -0.0170 | -0.0837 | -0.0190 | -0.1897 | -0.0866 | -0.1206 | -0.0081 | -0.0470 | +0.0519 | +0.0001 | -0.0706 | -0.1286 | -0.0980 | -0.2006 | -0.0650 | +0.0939 | +1.0000 | +0.0948 | +0.0071 | -0.2047 | -0.1936 | +0.0030 | -0.0815 | +0.0204 | +0.1192 | -0.0592 | -0.0026 | -0.0688 | -0.0392 | -0.0518 | +0.0327 | -0.0098 | -0.0001 | -0.0233 | -0.1117 |
| L- 34 | +0.0555 | -0.1073 | +0.1113 | +0.0314 | +0.0106 | -0.0107 | -0.0340 | +0.0741 | -0.0246 | -0.1844 | +0.0548 | +0.0256 | -0.0597 | +0.0378 | -0.0693 | -0.0315 | -0.0837 | +0.1047 | -0.0266 | +0.0415 | +0.0215 | -0.0223 | +0.0451 | -0.0297 | +0.0331 | +0.0181 | +0.0494 | -0.0140 | +0.0948 | +1.0000 | +0.0036 | +0.1106 | +0.0457 | -0.0023 | +0.0411 | -0.0226 | -0.0326 | +0.1171 | +0.0133 | +0.0256 | +0.0071 | -0.0093 | -0.0596 | -0.0067 | +0.0392 | -0.0040 | +0.0939 |
| S- 35 | -0.0141 | +0.0076 | +0.0118 | -0.0236 | -0.0024 | -0.0154 | -0.0188 | +0.0141 | -0.0184 | -0.0019 | +0.0242 | -0.0171 | +0.0456 | -0.0100 | -0.0239 | +0.0912 | -0.0185 | +0.0082 | +0.0153 | -0.0094 | +0.0157 | -0.0195 | -0.0314 | +0.0259 | +0.0546 | -0.0405 | -0.0012 | -0.0253 | +0.0071 | +0.0036 | +1.0000 | +0.0045 | +0.0219 | -0.0434 | +0.0002 | -0.0015 | +0.0021 | -0.0056 | +0.0242 | +0.0054 | +0.0316 | -0.0010 | +0.0142 | -0.0036 | -0.0074 | -0.0095 | +0.0043 |
| S- 36 | +0.0091 | +0.0763 | -0.0317 | -0.0402 | -0.0280 | +0.0495 | +0.0118 | +0.0133 | -0.0864 | +0.1292 | -0.1355 | +0.0476 | -0.0807 | -0.0424 | -0.0039 | -0.1012 | -0.1043 | -0.0891 | -0.0575 | -0.0155 | -0.0368 | -0.0065 | +0.0584 | -0.0851 | +0.0272 | -0.0553 | -0.0200 | -0.1289 | -0.2047 | +0.1106 | +0.0045 | +1.0000 | -0.1373 | -0.0080 | -0.0617 | -0.0090 | +0.0386 | -0.0701 | -0.0132 | -0.0510 | -0.0092 | -0.0197 | +0.0042 | -0.0215 | +0.0139 | -0.0081 | -0.0545 |
| E- 37 | -0.0213 | -0.0911 | -0.0199 | +0.0659 | +0.0177 | +0.0055 | +0.0386 | -0.0131 | -0.0415 | -0.0145 | -0.1306 | -0.0189 | -0.2742 | -0.0186 | -0.1051 | -0.1850 | -0.0202 | -0.0758 | +0.0662 | -0.0191 | +0.0578 | -0.0669 | -0.0712 | -0.0256 | -0.1526 | -0.1059 | -0.0214 | +0.0169 | -0.1936 | +0.0457 | +0.0219 | -0.1373 | +1.0000 | +0.0771 | -0.0744 | +0.0000 | +0.0516 | -0.0168 | -0.1125 | +0.0439 | -0.0248 | -0.0072 | +0.0190 | -0.0040 | -0.0866 | +0.0853 | -0.0455 |
| L- 38 | -0.0532 | -0.0267 | -0.0018 | -0.0952 | -0.0067 | -0.0148 | -0.0749 | -0.0825 | +0.0013 | +0.0279 | -0.0713 | -0.0744 | +0.0063 | +0.0174 | +0.0675 | +0.0166 | -0.0404 | -0.0893 | -0.0064 | +0.0292 | +0.0081 | -0.0413 | +0.0765 | +0.0741 | -0.0151 | +0.0094 | -0.1021 | +0.0644 | +0.0030 | -0.0023 | -0.0434 | -0.0080 | +0.0771 | +1.0000 | +0.0372 | -0.0018 | +0.0381 | +0.1152 | -0.0312 | +0.1043 | +0.2398 | +0.0843 | +0.0068 | +0.0908 | -0.0574 | -0.0937 | -0.0347 |
| G- 39 | -0.0040 | +0.0811 | +0.0473 | -0.0215 | -0.0347 | -0.0050 | +0.1082 | +0.0285 | -0.0592 | -0.0224 | -0.0560 | +0.0023 | -0.0655 | -0.0148 | -0.0233 | +0.0232 | +0.0096 | +0.0018 | +0.0245 | -0.0359 | -0.0074 | -0.0273 | +0.0144 | -0.0560 | +0.0234 | -0.0576 | +0.0056 | +0.0207 | -0.0815 | +0.0411 | +0.0002 | -0.0617 | -0.0744 | +0.0372 | +1.0000 | -0.0071 | -0.0449 | -0.0755 | -0.0380 | -0.0525 | -0.0175 | -0.0119 | +0.0389 | +0.0666 | -0.0265 | -0.0114 | -0.1233 |
| L- 40 | +0.0075 | -0.0215 | -0.0345 | -0.0133 | -0.0508 | +0.0083 | -0.0184 | -0.0140 | +0.0340 | +0.0165 | +0.0259 | +0.0127 | +0.0006 | -0.0266 | -0.0318 | -0.0028 | +0.0256 | -0.0089 | +0.0281 | -0.0021 | +0.0448 | -0.0599 | -0.0113 | -0.0177 | +0.0281 | +0.0374 | -0.0254 | -0.0300 | +0.0204 | -0.0226 | -0.0015 | -0.0090 | +0.0000 | -0.0018 | -0.0071 | +1.0000 | +0.0216 | +0.0011 | +0.0074 | +0.0457 | +0.0056 | -0.0327 | -0.0398 | +0.0301 | -0.0272 | -0.0637 | -0.0203 |
| N- 41 | -0.0267 | +0.0679 | -0.0069 | -0.0162 | -0.0276 | +0.1508 | +0.1353 | -0.0571 | +0.0033 | -0.1603 | +0.0090 | +0.1671 | +0.0384 | -0.1675 | +0.0360 | +0.0684 | -0.0316 | +0.0636 | -0.0234 | -0.0215 | -0.2278 | +0.0103 | -0.1752 | -0.0907 | +0.1520 | +0.1765 | +0.0114 | +0.0121 | +0.1192 | -0.0326 | +0.0021 | +0.0386 | +0.0516 | +0.0381 | -0.0449 | +0.0216 | +1.0000 | -0.0955 | -0.0602 | -0.0604 | -0.0155 | -0.0076 | -0.0555 | +0.2183 | -0.2873 | -0.0833 | -0.0194 |
| E- 42 | -0.0037 | +0.0571 | -0.0942 | -0.0081 | -0.1680 | +0.2059 | +0.0481 | -0.0366 | +0.0082 | +0.0747 | -0.0449 | +0.0839 | -0.0274 | -0.1155 | -0.0389 | +0.0116 | +0.1309 | -0.0064 | -0.0804 | -0.0304 | -0.0672 | +0.1562 | -0.1815 | -0.0702 | -0.0107 | -0.0649 | -0.2956 | -0.1231 | -0.0592 | +0.1171 | -0.0056 | -0.0701 | -0.0168 | +0.1152 | -0.0755 | +0.0011 | -0.0955 | +1.0000 | -0.0000 | -0.2008 | -0.0714 | +0.0797 | +0.0347 | -0.0908 | -0.2261 | +0.1300 | -0.0540 |
| A- 43 | -0.0516 | -0.1612 | -0.0797 | +0.0079 | +0.1840 | +0.0793 | +0.0903 | +0.0010 | +0.0481 | -0.0474 | -0.1426 | +0.0935 | -0.1454 | +0.1228 | -0.0257 | -0.0378 | -0.0824 | +0.0101 | +0.0337 | +0.0195 | -0.0542 | -0.0524 | -0.0617 | +0.1248 | -0.0427 | +0.0109 | -0.0657 | -0.0392 | -0.0026 | +0.0133 | +0.0242 | -0.0132 | -0.1125 | -0.0312 | -0.0380 | +0.0074 | -0.0602 | -0.0000 | +1.0000 | -0.0534 | +0.0053 | -0.0373 | -0.0093 | -0.0395 | -0.0905 | +0.0706 | -0.0968 |
| Q- 44 | +0.0029 | +0.0284 | -0.0157 | -0.0566 | -0.0840 | +0.0420 | +0.0066 | +0.0489 | -0.0236 | +0.0138 | -0.0226 | +0.0424 | -0.0304 | -0.1117 | -0.0041 | -0.0210 | +0.0149 | +0.0429 | -0.1012 | -0.0222 | -0.0701 | +0.2679 | -0.0992 | -0.0959 | +0.0070 | +0.0009 | +0.0591 | -0.1030 | -0.0688 | +0.0256 | +0.0054 | -0.0510 | +0.0439 | +0.1043 | -0.0525 | +0.0457 | -0.0604 | -0.2008 | -0.0534 | +1.0000 | -0.0826 | -0.1691 | +0.0948 | +0.0194 | +0.0488 | -0.0412 | +0.0101 |
| I- 45 | +0.0086 | -0.0151 | -0.0140 | +0.0123 | -0.0245 | +0.0154 | +0.0531 | +0.0489 | +0.0321 | +0.0120 | -0.0230 | +0.0389 | +0.0233 | +0.0023 | +0.0384 | -0.0386 | +0.0679 | +0.0135 | -0.0141 | -0.0253 | +0.0245 | +0.0729 | +0.0531 | -0.0732 | +0.0164 | +0.0446 | +0.0328 | +0.0378 | -0.0392 | +0.0071 | +0.0316 | -0.0092 | -0.0248 | +0.2398 | -0.0175 | +0.0056 | -0.0155 | -0.0714 | +0.0053 | -0.0826 | +1.0000 | -0.0313 | +0.0069 | -0.0235 | +0.0402 | +0.0182 | +0.0097 |
| K- 46 | +0.0130 | +0.0348 | -0.0171 | -0.0204 | +0.1027 | +0.0870 | -0.0117 | +0.0739 | +0.0333 | +0.0086 | +0.0225 | +0.0529 | -0.0048 | +0.0419 | -0.0080 | +0.0039 | +0.0155 | +0.1009 | +0.0430 | -0.0524 | +0.1355 | -0.2554 | -0.0317 | -0.1368 | +0.0681 | +0.0649 | -0.0413 | +0.0347 | -0.0518 | -0.0093 | -0.0010 | -0.0197 | -0.0072 | +0.0843 | -0.0119 | -0.0327 | -0.0076 | +0.0797 | -0.0373 | -0.1691 | -0.0313 | +1.0000 | +0.1122 | +0.0279 | +0.3527 | -0.1103 | +0.0722 |
| I- 47 | +0.0541 | +0.0049 | +0.0312 | -0.0219 | +0.0972 | +0.0505 | +0.0330 | -0.0188 | -0.0496 | +0.0358 | +0.0139 | +0.0691 | +0.0392 | -0.0075 | +0.0285 | -0.0261 | +0.0866 | -0.0405 | +0.0221 | -0.0680 | +0.0318 | +0.0206 | -0.0686 | +0.0440 | +0.0724 | +0.0198 | -0.0051 | -0.0400 | +0.0327 | -0.0596 | +0.0142 | +0.0042 | +0.0190 | +0.0068 | +0.0389 | -0.0398 | -0.0555 | +0.0347 | -0.0093 | +0.0948 | +0.0069 | +0.1122 | +1.0000 | -0.0276 | -0.0362 | +0.0725 | +0.0046 |
| Q- 50 | -0.0198 | -0.1751 | -0.0450 | +0.0443 | +0.0531 | +0.0380 | -0.0489 | +0.0494 | -0.0437 | +0.0306 | +0.0214 | -0.0497 | +0.0107 | +0.1378 | -0.1532 | +0.0069 | +0.0132 | +0.0287 | +0.0237 | +0.1700 | -0.0170 | +0.0137 | -0.0936 | +0.0496 | -0.1000 | -0.0350 | -0.1057 | -0.1725 | -0.0098 | -0.0067 | -0.0036 | -0.0215 | -0.0040 | +0.0908 | +0.0666 | +0.0301 | +0.2183 | -0.0908 | -0.0395 | +0.0194 | -0.0235 | +0.0279 | -0.0276 | +1.0000 | +0.1183 | +0.3128 | +0.0259 |
| K- 52 | -0.0554 | -0.0799 | -0.0155 | +0.0318 | -0.0521 | -0.0269 | +0.0687 | -0.0867 | +0.0621 | +0.0332 | -0.1197 | -0.0694 | -0.0265 | -0.2737 | +0.0430 | +0.0209 | -0.0198 | -0.0262 | -0.0098 | +0.0402 | +0.0164 | +0.0492 | -0.1286 | +0.0300 | -0.0518 | +0.0210 | +0.0778 | +0.0177 | -0.0001 | +0.0392 | -0.0074 | +0.0139 | -0.0866 | -0.0574 | -0.0265 | -0.0272 | -0.2873 | -0.2261 | -0.0905 | +0.0488 | +0.0402 | +0.3527 | -0.0362 | +0.1183 | +1.0000 | -0.0423 | -0.1038 |
| A- 54 | +0.0609 | +0.0435 | +0.0328 | +0.0035 | +0.0844 | -0.0379 | +0.0725 | -0.0595 | -0.0204 | +0.0380 | -0.0221 | +0.0185 | -0.0089 | -0.1485 | +0.0457 | +0.0336 | +0.0401 | -0.0268 | -0.0005 | -0.0401 | -0.0404 | -0.0004 | +0.0604 | -0.0853 | +0.0916 | +0.1065 | -0.0093 | +0.1546 | -0.0233 | -0.0040 | -0.0095 | -0.0081 | +0.0853 | -0.0937 | -0.0114 | -0.0637 | -0.0833 | +0.1300 | +0.0706 | -0.0412 | +0.0182 | -0.1103 | +0.0725 | +0.3128 | -0.0423 | +1.0000 | +0.0287 |
| I- 56 | -0.0348 | +0.1116 | +0.0228 | +0.0713 | +0.0371 | +0.0018 | +0.0099 | -0.0035 | +0.0109 | +0.0239 | -0.0139 | -0.0674 | -0.1286 | -0.0307 | -0.0488 | +0.0091 | -0.1099 | -0.0448 | +0.1323 | -0.0912 | -0.1541 | -0.0064 | -0.0610 | -0.0090 | +0.0296 | +0.1052 | +0.0009 | +0.0413 | -0.1117 | +0.0939 | +0.0043 | -0.0545 | -0.0455 | -0.0347 | -0.1233 | -0.0203 | -0.0194 | -0.0540 | -0.0968 | +0.0101 | +0.0097 | +0.0722 | +0.0046 | +0.0259 | -0.1038 | +0.0287 | +1.0000 |