LowComplexity: Sequence analysis software

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Main site (Novosibirsk): http://wwwmgs2.bionet.nsc.ru:8080/low_complexity/

Mirror-site (University of California, Irvine): http://emj-pc.ics.uci.edu:8080/low_complexity/

LZcomposer software (Novosibirsk): http://wwwmgs.bionet.nsc.ru/mgs/programs/lzcomposer/

Analysis of genomic sequences issues the challenge to search for the regions with the low text complexity, which could be functionally important. Several numerical measures of text complexity including combinatorial and linguistic ones, together with complexity estimation by modified Lempel-Ziv algorithm, are implemented in a software tool presented here. The software developed enables to search for low complexity regions in long sequences. In addition, it estimates complexity of groups of aligned sequences.

This resource has been developed in Institute of Cytology and Genetics, based on methods developed in Sobolev Institute of Mathematics, Novosibirsk, Russia. Please send any comments to Yury Orlov