Exhaustive sorting out of characteristics


For each site, the system ACTIVITY analyzes all the possible combinations of the oligonucleotides Z of the length m with all the weight functions w(i) considered. By analyzing the statistical characteristics of the sites, for each oligonucleotide Z of the length m, 180 functions w(i), each characterized by solo extremum (minimum or maximum) with specific location and shape, were considered. Under the fixed combination <Z,m,w>, for each sequence S, a weighted concentration of oligonucleotide XZmw(S) is calculated by the equation (2). Analogously, for the conformational and physical-chemical features, the exhaustive sorting of all possible combinations <q,a,b> is performed. For each combination, the value Xqab(S) is calculated by the equation (3).