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CLOCK-TRRD

Genes, controlling circadian rhythm, and genes with circadian expression
is developed by  Tamara M. Khlebodarova


 
 
 
 
 
 

Transcription factors

 

Gene name

Gene name synonym

Organism

TRRD AC

Period circadian protein 1 

PER1, period homolog 1 (Drosophila), Circadian pacemaker protein Rigui, RIGUI, PER

Homo sapiens

A01598

Period circadian protein 1

PER1,  period homolog 1 (Drosophila), Circadian pacemaker protein Rigui, RIGUI, PER

Mus musculus

A01634

Period circadian protein 1 

PER1, period homolog 1 (Drosophila)

Rattus norvegicus

A01667

Period circadian protein 2

PER2,  period homolog 2 (Drosophila)

Mus musculus

A01627

Period circadian protein 2 

PER2,  period homolog 2 (Drosophila)

Rattus norvegicus

A01668

Period circadian protein 2

PER2,  period homolog 2 (Drosophila)

Gallus gallus

A01686

Period circadian protein 3

PER3,  period homolog 3 (Drosophila)

Mus musculus

A01659

period 

PER, Clock-6 protein,  CLK-6

Drosophila melanogaster

A01638

Brain and muscle ARNT-like 1 

BMAL1, Member of PAS protein 3, BMAL1b, MOP3, BHLH-PAS protein, JAP3, ARNTL, Arnt3, aryl hydrocarbon receptor nuclear translocator-like

Rattus norvegicus

A01625

Brain and muscle ARNT-like 1 

BMAL1, Member of PAS protein 3, BMAL1b, MOP3, BHLH-PAS protein, JAP3, ARNTL, Arnt3

Mus musculus

A01629

cycle

CYC, Brain and muscle ARNT-like 1, BMAL1, MOP3 , CG8727

Drosophila melanogaster

A01645

aryl hydrocarbon receptor nuclear translocator-like

ARNTL,  BMAL1, Brain and muscle ARNT-like 1 gene, Member of PAS protein 3, MOP3, BHLH-PAS protein JAP3, JAP3, Arnt3, TIC

Gallus gallus

A01650

aryl hydrocarbon receptor nuclear translocator-like2

ARNTL2,  BMAL2

Homo sapiens

A01757

Circadian locomoter output cycles kaput protein  

clock homolog (mouse), KIAA0334, Clock (mouse) homolog, hCLOCK

Homo sapiens

A01758

Circadian locomoter output cycles kaput protein 

mCLOCK

Mus musculus

A01628

Circadian locomoter output cycles kaput protein 

CLOCK, dPAS1, CLK, JRK, PAS1

Drosophila melanogaster

A01644

Circadian locomoter output cycles kaput protein 

CLOCK

Gallus gallus

A01651

BHLH-PAS transcription factor MOP9 

MOP9

Mus musculus

A01632

D site albumin promoter binding protein

DBP, Albumin d box-binding protein,  D-site-binding protein

Mus musculus

A01633

D site albumin promoter binding protein 

DBP, Albumin d box-binding protein,  D-site-binding protein

Rattus norvegicus

A01635

Member of PAS protein 4 

MOP4, NPAS2, neuronal PAS domain protein 2, Neuronal PAS2, Member of PAS protein

Gallus gallus

A01653

timeless homolog (Drosophila)

TIM, TIM1, hTIM 

Homo sapiens

A01656

aryl hydrocarbon receptor 

AHR, Ah receptor, AhR

Rattus norvegicus

A01662

aryl hydrocarbon receptor nuclear translocator

Dioxin receptor, nuclear translocator,  Hypoxia-inducible factor 1 beta, HIF-1 beta,  HIF1beta

Rattus norvegicus

A01663

 bZIP protein E4BP4

cE4BP4,  NFIL3

Gallus gallus

A01685

Timeless

TIM

Drosophila melanogaster

A01682

timeless homolog (Drosophila) 

TIM1, TIM,  mTIM1, timeless (Drosophila) homolog

Mus musculus

A01691

Takeout 

TO

Drosophila melanogaster

A01683

cone-rod homeobox

CRX,  CORD2, CRD, cone rod dystrophy 2 

Rattus norvegicus

A01722

Circadianly Regulated Gene

Crg-1

Drosophila melanogaster

A01006

thyrotrophic embryonic factor

TEF

Rattus norvegicus

A01624

thyrotrophic embryonic factor

TEF

Mus musculus

A01626

Photoreceptors

 

Gene name

Gene name synonym

Organism

TRRD AC

Cryptochrome 

CRY, photolyase/blue-light receptor homolog, photolyase-like

Drosophila melanogaster

A01646

cryptochrome 2 

CRY2,  photolyase/blue-light receptor homolog, photolyase-like

Homo sapiens

A01655

cryptochrome 1

CRY1, photolyase/blue-light receptor homolog, photolyase-like,  Phll1

Mus musculus

A01657

cryptochrome 2

CRY2, photolyase/blue-light receptor homolog, photolyase-like

Mus musculus

A01658

Pineal opsin

POPS, P-opsin, Pinopsin, Pineal gland-specific opsin

Gallus gallus

A01756

Enzymes of serotonin/melatonin synthesis

 

Gene name

Gene name synonym

Organism

TRRD AC

arylalkylamine N-acetyltransferase

AANAT,  SNAT, Serotonin N-acetyltransferase, Aryalkylamine, N-acetyltransferase, AA-NAT, Serotonin acetylase

Rattus norvegicus

A01665

arylalkylamine N-acetyltransferase

AANAT,  SNAT, Serotonin N-acetyltransferase, Aryalkylamine, N-acetyltransferase, AA-NAT, Serotonin acetylase

Danio rerio

A01647

arylalkylamine N-acetyltransferase

AANAT,  SNAT, Serotonin N-acetyltransferase, Aryalkylamine, N-acetyltransferase, AA-NAT, Serotonin acetylase

Esox lucius

A01648

arylalkylamine N-acetyltransferase 

AANAT,  SNAT, Serotonin N-acetyltransferase, Aryalkylamine, N-acetyltransferase, AA-NAT, Serotonin acetylase

Gallus gallus

A01684

tryptophan hydroxylase gene

TRPH, TPH

Esox lucius

A01649

Tryptophan 5-hydroxylase 

TPH, Tryptophan 5-monooxygenase, TRPH

Gallus gallus

A01652

arylalkylamine N-acetyltransferase

AANAT, SNAT, Serotonin N-acetyltransferase, Aryalkylamine N- acetyltransferase, AA-NAT, Serotonin acetylase

Oncorhynchus mykiss

A01660

tryptophan hydroxylase gene 

TPH,  TRPH

Oncorhynchus mykiss

A01661

Acetylserotonin O-methyltransferase

ASMT, ASMTY, ASMTX, hydroxyindole O-methyltransferase, HIOMT

Mus musculus

A01709

Acetylserotonin O-methyltransferase 

ASMT, ASMTY, ASMTX, hydroxyindole O-methyltransferase, HIOMT

Gallus gallus

A01725

Acetylserotonin O-methyltransferase

ASMT, ASMTY, ASMTX, hydroxyindole O-methyltransferase, HIOMT

Rattus norvegicus

A01761

Receptors

 

Gene name

Gene name synonym

Organism

TRRD AC

Patched protein homolog 1

PTC1, PTC, PTCH

Rattus norvegicus

A01666

Other enzymes

 

Gene name

Gene name synonym

Organism

TRRD AC

Mitogen-activated protein kinase 1 

MAPK1, extracellural signal-regulated protein kinase 2,  ERK2,  P42-MAPK, 42 kDa serine-threonine kinase, 41 kDa pineal protein, pp41

Gallus gallus

A01654

pineal night-specific ATPase 

PINA,  Copper-transporting ATPase 2, Copper pump 2, Wilson disease-associated protein homolog, ATP7B, WND

Rattus norvegicus

A01717

5-aminolevulinate synthase 1

ALAS1, 5-aminolevulinic acid synthase, delta-aminolevulinate synthase, delta-ala synthetase, ALAS-1, Alas-H

Mus musculus

A01643

5-aminolevulinate synthase 2

ALAS-E, delta-aminolevulinate synthase, delta-ala synthetase, ALAS-2, Alas2

Mus musculus

A01209

cholesterol 7-alpha-hydroxylase gene

CYP7, cholesterol 7alpha-monooxygenase gene, cytochrome P450 VII

Rattus norvegicus

A00411

Cytochrome P450, 2A4

CYP2A4, CYP2A-4, CYPIIA4, Testosterone 15-alpha-hydroxylase, Cyp15a1, steroid 15-alpha-hydroxylase, P450-15-alpha, P450-IIA3.1, D7Ucla4

Mus musculus

A01630

Cytochrome P450, 2A5

CYP2A5, CYP2A-5, CYPIIA5, coumarin 7-hydroxylase, P450-15-con, P450-IIA3.2, Cyp15a2, Coh

Mus musculus

A01631

Other genes

 

Gene name

Gene name synonym

Organism

TRRD AC

arginine vasopressin 

AVP,  Arg-vasopressin, neurophysin II, antidiuretic hormone, ADH, ARVP, AVRP, VP

Mus musculus

A01688

Nocturnin

 NOC, Rhythmic message 1, RM1

Mus musculus

A01689

Nocturnin

 NOC, Rhythmic message 1, RM1

Xenopus laevis

A01640

retinol binding protein 1, cellular

CRBP1, cellular retinol-binding protein 1, CRBP-1, CRABP-I, RBP-I, Rbp1

Mus musculus

A01641

arginine vasopressin 

AVP,  Arg-vasopressin, neurophysin II, antidiuretic hormone, ADH, ARVP, AVRP, VP

Homo sapiens

A01710

arginine vasopressin

AVP,  Arg-vasopressin, neurophysin II, antidiuretic hormone, ADH, ARVP, AVRP, VP

Rattus norvegicus

A01716

Hepatic angiopoietin-related protein

NG27, Hypothetical protein 425O18-1, Fibrinogen/angiopoietin-related protein, Angiopoietin-like protein, Angiopoietin-like 4, ANGPTL4, FARP, HARP, 425O18-1, 166

Mus musculus

A01642