Examples of sites from the system “ACTIVITY”

Site

Activity

Scale

Range

 

quantitative parameter

 

min

max

Cro-binding site

association rate constant

ln

19.1

19.9

CRP-binding site

CRP/DNA affinity

ln

-3.2

3.2

E. coli promoter

strength

-log

0.26

2.1

C-protein binding site

trancription activity

ln

-6.2

1.8

TATA box

lifetime

minute

1

185

TATA box

bend

degree

33

106

transcription signal INR

affinity

ln

-4.6

1.3

transcription signal OCT-1

trancription activity

ln

-2.3

0.63

transcription signal USF

affinity USF/DNA

ln

3.8

100

PE1B box (adjacent TATA box)

trancription activity

ln

-1.4

1.4

transcription signal IL-1

trancription activity

ln

-1.9

4.1

pre-mRNA 3’cleavage site

cleavage efficiency

%

3

289

pre-mRNA 5’splice site

cleavage efficiency

%

18

100

E. coli ribosome-binding site

translation activity

ln

0.0

8.06

2-aminopurine induced hotspots

mutability

ln

0.0

5.6

back