The functional sites of the same type can differ in activity by several orders of magnitude
Type |
no. | Sequence |
Activity |
| TBP/TATA-affinity (Yaest) | 1 | GGGGCTATAAAAGGGGGTGG |
6.7 |
| 2 | GCCTGCACAAATAGGGACGA |
2.0 |
|
| 3 | GTACCTATGGGTCTGCTGGT |
1 |
|
| CRO/DNA-affinity (E.coli) | 1 | TAATGTGAGTTAGCTCACTCAT |
90.9 |
| 2 | ATGAGTGAGCTAGCTCACTCAT |
9.1 |
|
| 3 | TAATGTAAGTTAGCTCACTCAT |
1 |
|
| 3’end pre-mRNA processions | 1 | UUCUACCGGAUCGUUGUGUUCGAGG |
12.6 |
| efficiency (SV40) | 2 | UUCUACCGGAUCGUUGAGUUCGAGG |
3.3 |
| 3 | UUCUACCGGAUCGUUUUGGUCGAGG |
1 |
|
| mutation fequency (E.coli) | 1 | CGCGTGGTGAACCAGGCCAGCCACG |
51.0 |
| 2 | GACATGGCACTCCAGTCGCCTTCCC |
10.0 |
|
| 3 | ACCACCATCAAACAGGATTTTCGCC |
1 |
|
| RecA/DNA affinity (E.coli) | 1 | CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC |
350.0 |
| 2 | GGCGGGCGGCGCGGCCGGGCGGCGGGCGCGCG |
26.0 |
|
| 3 | AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
1 |