ddG-Matrix: c-Myb transcription factor binding site on DNA

Input DNA Sequence :
from Screen:

from DB: Bases Available:
from File: File formats here.

Select one of Seven c-Myb site recognition models listed below:


(A) five prediction procedures optimized over the point mutation ddG magnitudes:

c-Myb: Low ddG decreases with Major Groove Inflexibility
c-Myb: Higher ddG's increases with Tilt
c-Myb: Point mutation ddG via Major Groove Inflexibility and Tilt
c-Myb: Additive ddG-matrix Score
c-Myb: Multiple mutation ddG via Point mutation ddG

(B) two additional prediction procedures adapted to the others c-Myb relevant systems:

c-Myb: Natural sites recognition by Multiple mutation ddG adapted to TRRD and TRANSFAC
c-Myb: SELEXed sites recognition by Multiple mutation ddG adapted to SELEX_DB

The Institute of Cytology and Genetics (Russia)

This resource has been developed in collaboration between
The Institute of Cytology and Genetics (Novosibirsk, Russia) and The Institute of Physical and Chemical Research, RIKEN (Thukuba, Japan)
that was supported by RFBR grant #98-07-90126 (Russia) and STA Fellow #499042 (Japan)

Author: Misha Ponomarenko, Ph.D.

Contributors: Julia Ponomarenko, Ms.D., Galina Orlova, Ph.D., Sergey Lavrushev, Ms.D., Anatoly Frolov, Ph.D.

Supervisors: Nikolay Kolchanov, Prof. and Akinori Sarai, Prof.