Prediction of mRNA translational activity (example of a LOW expression mammalian gene).

Prediction of mRNA translational activity (example of a LOW expression mammalian gene).

The sequence in the input field below is the 5'UTR of
human gene for insulin-like growth factor binding protein-1 (IGFBP1)
gene [EMBL ID: HSIGFBP1] (it was used in a training sample as a LOW expression gene).

Input DNA Sequence :
from Screen:
atcggccacc gccatcccat ccagcgagca tctgccgccg cgccgccgcc accctcccag agagcactgg ccaccgctcc accatcactt gcccagagtt tgggccaccg cccgccgcca ccagcccaga gagcatcggc ccctgtctgc tgctcgcgcc tggag
from DB: Bases Available:
from File: File formats here.

Example Related Paper

Expert Weights (0-10 are valid)
1. Translation INCREASES with DECREASING the Leader length
2. Translation INCREASES with DECREASING [G] content
3. Translation INCREASES with INCREASING [T] content
4. Translation INCREASES with DECREASING [G+C] content
5. Translation INCREASES with DECREASING [AUG]:[-AUG] disbalance
6. Translation INCREASES with INCREASING [G]:[C+T] ratio
7. Translation INCREASES with INCREASING [A]:[T] ratio
8. Translation INCREASES with INCREASING [AUG]:[-AUG] ratio
9. Translation INCREASES with DECREASING [G]:[C+T] disbalance
10. Translation INCREASES with DECREASING [A]:[T] disbalance
11. Translation INCREASES with DECREASING [AUG] content
12. Translation INCREASES with DECREASING [AUG] framed
13. Translation INCREASES with DECREASING [AUG] optimized
14. Translation INCREASES depends on the "-3 position" rule
15. Translation INCREASES with DECREASING [AUG] "-3"-ruled
16. Translation INCREASES with INCREASING [T] content of [-35;-1]
17. Translation INCREASES with INCREASING [TS] content of [-35;-1]
18. Translation INCREASES with DECREASING [SCV] content of [-35;-1]
19. Translation INCREASES with INCREASING [WxHK] content of [-35;-1]
20. Translation INCREASES with INCREASING High-consensus matches
21. Translation INCREASES with DECREASING Low-consensus matches
22. Translation INCREASES with INCREASING High-ShortFreqMatr
23. Translation INCREASES with INCREASING High/Low 1bp(ATGC)-FreqRatio
24. Translation INCREASES with INCREASING High/Low 2bp(ATGC)-FreqRatio
25. Translation INCREASES with INCREASING High/Low 1bp(KM)-FreqRatio
26. Translation INCREASES with INCREASING High/Low 2bp(KM)-FreqRatio
27. Translation INCREASES with INCREASING High/Low 3bp(KM)-FreqRatio
28. Translation INCREASES with INCREASING High/Low 4bp(KM)-FreqRatio
29. Translation INCREASES with INCREASING High/Low 1bp(RY)-FreqRatio
30. Translation INCREASES with INCREASING High/Low 2bp(RY)-FreqRatio
31. Translation INCREASES with INCREASING High/Low 3bp(RY)-FreqRatio
32. Translation INCREASES with INCREASING High/Low 4bp(RY)-FreqRatio
33. Translation INCREASES with INCREASING High/Low 1bp(WS)-FreqRatio
34. Translation INCREASES with INCREASING High/Low 2bp(WS)-FreqRatio
35. Translation INCREASES with INCREASING High/Low 3bp(WS)-FreqRatio
36. Translation INCREASES with INCREASING High/Low 4bp(WS)-FreqRatio
37. Translation INCREASES with INCREASING High/Low 3bp(ATGCx)FreqRatio
38. Translation INCREASES with INCREASING High/Low 3bp(KxM)-FreqRatio
39. Translation INCREASES with INCREASING High/Low 5bp(KxM)-FreqRatio
40. Translation INCREASES with INCREASING High/Low 7bp(KxM)-FreqRatio
41. Translation INCREASES with INCREASING High/Low 3bp(RxY)-FreqRatio
42. Translation INCREASES with INCREASING High/Low 5bp(RxY)-FreqRatio
43. Translation INCREASES with INCREASING High/Low 7bp(RxY)-FreqRatio
44. Translation INCREASES with INCREASING High/Low 3bp(WxS)-FreqRatio
45. Translation INCREASES with INCREASING High/Low 5bp(WxS)-FreqRatio
46. Translation INCREASES with INCREASING High/Low 7bp(WxS)-FreqRatio
Prediction will be the mean value of the Expert estimates with their weights

Author AV.Kochetov
Contributors:Misha Ponomarenko, Anatoly Frolov
Leader: Nikolay A. Kolchanov
Collaboration: L.L. Kisselev (Moscow)