PHYSICO-CHEMICAL DNA
PROPERTIES USED FOR PREDICTION OF FUNCTIONAL SITES ACTIVITY

 

Parameter

Unit

Min

Max

Clash strength (clash)

f

0.00

2.53

Bending mobility to minor groove

m

1.02

1.27

Bending mobility to major groove

m

0.99

1.18

Persistent length

20

130

Melting temperature

oC

36.7

136.1

Probability of nucleosome binding

%

1

18

Entropy change

kcal/mol

-11.8

-5.6

Enthalpy change

cal/mol/K

-28.4

-15.2

Free energy change

kcal/mol

-2.8

-0.9

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