rSNP_Report Help
rSNP_Report database presents the protocols of the rSNP_Tools applet predictions, which are confirmed experimentally and represented as hypertexts.
Columns TF-site Score, the known 41 transcription factor binding sites taken into account. Database MATRIX containing the weight frequency matrices and Recognition Tools for these TF-sites is used.
Columns DNA-sequence variants, the TF-sites recognition Score values, which refer to the wild-type sequence and to the mutated sequence. These sequences are documented in the rSNP_DB database.
Area DNA/protein-Binding, X-sites, which simulate the mutation-caused alterations in the pattern of DNA binding to nuclear proteins.
Columns Euclidean distances, Euclidean distances between the recognition Scores of the known TF sites (Columns TF-site Score) and X-simulated ones (Area DNA/protein-Binding).
Columns Student's t-scaled similarity, Student's t-scaled similarity between the known TF sites (Columns TF-site Score) and X-simulated ones (Area DNA/protein-Binding) calculated by using Euclidean distances between them (Columns Euclidean distances).
Column Res, prediction {X=TF-site}.
Area Robustness, control test of the prediction {X=TF-site} for robustness, by using the standard STATISTICA package for combinatorial vary {similarity scale (column-listed); cluster-analysis method (line-listed)}.