Blood

Query  to the GeneNet database:
genes expressing in BLOOD
Select species: AllHumanMurine
Select GeneNet SRS table: GeneProtein
         

Query  to the TRRD database:
genes expressing in BLOOD
Select species:   All       Human     Murine   
           

Function: convey nutrients, oxygen to cells, carrying wastes, carbon dioxide away from the cells, carrying hormones and other regulatory agents, homeostatic role based on its thermoregulatory and buffering capacity, protection from infections, foreign cells and proteins.

Location: cardiovascular system.

Origin: mesenhyme

Plasma

Function: convey nutrients, carrying wastes, carrying hormones and other regulatory agents, homeostatic role based on its thermoregulatory and buffering capacity, protection from infections, foreign cells and proteins.

Location: cardiovascular system.

Composition: water 91-92%, proteins (fibrinogens, globulins, albumin) 7-8%, other solutes 1-2%, electrolytes, nonprotein nitrogen substances (urea, uric acid, creatin...), nutrients (glucose, lipids, amino acids), blood gasses (oxygen, carbon dioxide, nitrogen), regulatory substances (hormones, enzymes)

Formed elements (blood cells and cellular elements)

Red blood cells (erythrocytes)

Query  to the TRRD database:
genes expressing in ERYTHROID CELLS
Select species:            
All       Human     Murine   
                  

Function: within the bloodstream, binding oxygen and, in exchange, binding carbon dioxide.

Composition: hemoglobin: polypeptide chains with iron-containing heme group, degradation in spleen and liver.

White blood cells (leukocytes)

Query  to the TRRD database:
genes expressing in WHITE BLOOD CELLS
Select species:            
All       Human     Murine   
                  

Function: transients within the blood, leave the blood through the walls of vessels to enter the specific sites of activity in the connective tissue

Function: phagocytosis of some bacteria, early phases of acute inflammation (pus).

Composition: bacteriostatic and bacteriocidal agents (lysozyme), alkaline phosphatases in specific granules, peroxidase and lysosomal enzymes in azurophilic granules.

Function: phagocytosis of antigen-antibody complexes, allergic reactions.

Composition: major basic protein, arylsulfatase, histaminase, peroxidase and other hydrolytic enzymes in granules.

Function: bind the antibody (IgE), release the vasoactive agents from the granules in association with hypersensitivity and anaphylaxis.

Composition: hydrolytic enzymes, heparan sulfate, histamine and slow-reacting substance (SRS) of anaphylaxis in granules.

Function: immature neutrophils

Function: recirculating immunocompitent cells; precursors of plasma cells, of cytotoxic T lymphocytes (killer, helper, supressor), of memory cells; hemopoietic stem cells (megakaryocyte); natural killer cells; immune reactions, late phases of acute inflammation, chronic inflammation.

Function: precursors of various phagocytes of the mononuclear phagocytic system: connective tissue macrophages, osteoclasts, alveolar macrophages, Kupffer cells in liver, macrophages of lymph nodes, spleen, bone marrow.

Function: clot formation, retraction and, presumably, dissolution.

Composition: serotonin and thromboplastin in very dense granules; lysosomal enzymes in a -lysosomal granules.

Origin: bone marrow, megakaryocytes.